DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GAPsec and sgsm3

DIOPT Version :9

Sequence 1:	NP_648245.2	Gene:	GAPsec / 38987	FlyBaseID:	FBgn0035916	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_998495.1	Gene:	sgsm3 / 406635	ZFINID:	ZDB-GENE-040426-2635	Length:	755	Species:	Danio rerio

Alignment Length:	387	Identity:	65/387 - (16%)
Similarity:	123/387 - (31%)	Gaps:	139/387 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 QLRKLAFNGVPDVQSFRALSWKLLLGYLGPRRSSWTTTLAQKRALYKQFIEELVLPPGHSSNRAS 90
            :||.|...|:|  .|.|...|..|.|.|..:|:|..:        |::.::       :|||
Zfish   107 RLRSLVLGGIP--HSMRPQLWMRLSGALQKKRTSDIS--------YREIVK-------NSSN--- 151

  Fly    91 VDGGDGDKVDSGGVGLQDHPLSEGPESAWNTFFNDNEFLLQIDKDVRRLCPDISFFQQPTDYPCE 155
                                             :|.....||:||:.|..|..:.|.
Zfish   152 ---------------------------------DDTTAAKQIEKDLLRTMPTNACFN-------- 175

  Fly   156 IVVHSKGEHGRRLHERVVPAVLSSANVERKGLGMTKINLITKRSVENYAAMEEGQEAHWEVVQRI 220
                                .|:|..|.:                                ::|:
Zfish   176 --------------------TLTSVGVPK--------------------------------LRRV 188

  Fly   221 LFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDLTYRAHAEADCFFCFTALMSEI--RDFFIKTL 283
            |...|.|.|..||.||...:|..:...:           .|.|..:...||:.::  ..:|..||
Zfish   189 LRGLAWLYPDIGYCQGTGMVVSCLLLFL-----------EEEDALWMMCALIEDLLPPSYFSSTL 242

  Fly   284 DDAEGGIKFMMARLSNMLKSKDLSIYELLRSQELHPQYYSFRWLTLLLSQEFPLPDVLRIWDSVF 348
            ...:...:.:...:...|...|    :||:..::.....:..|.....:....:..:|||||.:|
Zfish   243 LGVQTDQRVLRQLIVQYLPRLD----KLLQEHDIELSLITLHWFLTAFASVVDIRILLRIWDLLF 303

  Fly   349 ADEQRFDFLIKICCSMILIQREAILENDFASNV-KLLQNYP------PIDINVVIAHAGSLA 403
            .:...  .|.::...|:.|:.:.::.::.:::: ..|.:.|      ...:...:..||||:
Zfish   304 YEGSM--VLFQVTLGMLKIKEDELVSSENSASIFNTLSDLPSQLEDGAAVLGEAVRLAGSLS 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	31/183 (17%)
sgsm3	NP_998495.1	TBC	112..326	CDD:214540	56/343 (16%)
		SH3_SGSM3	488..540	CDD:212747
		RUN	567..720	CDD:280855
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810