DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GAPsec and CG7324

DIOPT Version :9

Sequence 1:	NP_648245.2	Gene:	GAPsec / 38987	FlyBaseID:	FBgn0035916	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_649305.1	Gene:	CG7324 / 40361	FlyBaseID:	FBgn0037074	Length:	1291	Species:	Drosophila melanogaster

Alignment Length:	374	Identity:	69/374 - (18%)
Similarity:	113/374 - (30%)	Gaps:	139/374 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 SWTTTLAQKRALYKQFIEELVLPPGHSSNRASV---DGGDG------------------DK---- 98
            ||:...|.......||..|::........|...   |.|.|                  ||
  Fly   406 SWSKQTALMNTFKTQFSAEIIQKQEEKMVRWEAHFRDFGRGIGMFRTTDVINLIVEGIPDKLRQE 470

  Fly    99 ---VDSGGV-------GLQDHPLSEGPESAWNTFFNDNEFLLQIDKDVRRLCPDISFFQQPTDYP 153
               :.||.:       ||.: .|.|......|.|.:|     :||:|:.|..|:...||. ||
  Fly   471 IWLIFSGAIHDKEMNPGLYE-DLVEKAACIKNCFAHD-----EIDRDLPRSLPEHPAFQS-TD-- 526

  Fly   154 CEIVVHSKGEHGRRLHERVVPAVLSSANVERKGLGMTKINLITKRSVENYAAMEEGQEAHWEVVQ 218
                                            |:|                           .::
  Fly   527 --------------------------------GIG---------------------------ALR 532

  Fly   219 RILFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDLTYRAHAEADCFFCFTALMSEIRDFFIKTL 283
            |:|..||..||..||.|.|| ||..::.:...          |.:.|:...:|...:...:.|
  Fly   533 RVLQAYALRNPQVGYCQAMN-IVSSVFLLFCD----------EENAFWMLASLCENLLPDYYK-- 584

  Fly   284 DDAEGGIKFMMARLSNMLKS---------KDLSIYELLRSQELHPQYYSFRWLTLLLSQEFPLPD 339
             |...|.:.....|:.::::         :.|.:.:::          |..|...:.........
  Fly   585 -DKVVGAQIDQGVLNELVETHLPDLHGHLEQLGVIKMI----------SISWFLTIFMSVISYES 638

  Fly   340 VLRIWDSVFADEQRFDFLIKICCSMILIQREAILE-NDFASNVKLLQNY 387
            .|.|.|..|.:..:..|:|.:  .:|...|:.:|. .|....:.:||||
  Fly   639 SLHILDCFFYEGAKIIFMISL--QIIEWNRDKLLICQDDGEAMLVLQNY 685

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	31/190 (16%)
CG7324	NP_649305.1	PH-GRAM1_TCB1D8_TCB1D9_family	147..249	CDD:275404
		PH-GRAM2_TCB1D9_TCB1D9B	293..389	CDD:270161
		TBC	462..670	CDD:214540	53/301 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456580
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22957
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840