Protein Alignment GAPsec and Tbc1d2

DIOPT Version :9

• Sequence 1: NP_648245.2
• Gene: GAPsec / 38987
• FlyBaseID: FBgn0035916
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: XP_006538109.1
• Gene: Tbc1d2 / 381605
• MGIID: 2652885
• Length: 923
• Species: Mus musculus
• Alignment Length: 391
• Identity: 78/391 - (19%)
• Similarity: 128/391 - (32%)
• Gaps: 121/391 - (30%)

  Fly     2 SIFKARVKEFED--VLAGPQ-DLIDLKQLRKLAFNGVPDVQSFRALSWKLLL--GYLGPRRSSWT 61
            |:..:.|.|::|  .|..|. ::.|||.|.|        :|:....|..||.  ....|.|..|.
Mouse   546 SVGLSPVSEYDDYGFLTVPDYEMEDLKLLAK--------IQALEVRSHHLLAHEAVERPLRDRWA 602

  Fly    62 T-TLAQKRALYKQFIEELVLPPGHSSNRASVDGGDGDKVDSGGVGLQDHPLSEGPESAWNTFFND 125
            | |.....|..||.:            ||.|                  |....|. .|...
Mouse   603 TLTELTPSAELKQLL------------RAGV------------------PREHRPR-VWRWL--- 633

  Fly   126 NEFLLQIDKDVRRLCPDISFFQQPTDYPCEIVVHSKG-EHGRRLHERVVPAVLSSANVERKGLGM 189
                  :.:.||.|       |.|..|. |::...:. ||         ||.
Mouse   634 ------VHRRVRHL-------QAPGCYQ-ELLARGRACEH---------PAA------------- 662

  Fly   190 TKINLITKRSVENYAAMEEGQEAHWEVVQRILFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDL 254
            .:|.|...|:............:..:.::|:|..::..||..||.||:|.:......|:..
Mouse   663 RQIELDLNRTFPTNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLED---- 723

  Fly   255 TYRAHAEADCFFCFTALMSEI--RDFFIKTLDDAEGGIKFMMARLSNML---------KSKDLSI 308
                  |...|:|..|::..|  .:::.|||..::...:.:...||..|         ...|||:
Mouse   724 ------EESAFWCLVAIVETILPAEYYSKTLTASQVDQRVLQDLLSEKLPRLTAHLGQHRVDLSL 782

  Fly   309 YELLRSQELHPQYYSFRWLTLLLSQEFPLPDVLRIWDSVFADEQRFDFLIKICCSMILIQREAIL 373
                         .:|.|..::.:.......:||:||:...:..:..|  :...::.....||||
Mouse   783 -------------ITFNWFLVVFADSLISDILLRVWDAFLYEGTKVVF--RYALAIFKYNEEAIL 832

  Fly   374 E 374
            :
Mouse   833 Q 833

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	36/192 (19%)
Tbc1d2	XP_006538109.1	PH_TBC1D2A	45..146	CDD:269966
		PRK14951	<192..404	CDD:237865
		COG4913	<300..>565	CDD:227250	5/18 (28%)
		TBC	620..832	CDD:214540	51/294 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810