DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GAPsec and Sgsm3

DIOPT Version :9

Sequence 1:	NP_648245.2	Gene:	GAPsec / 38987	FlyBaseID:	FBgn0035916	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_942082.2	Gene:	Sgsm3 / 362963	RGDID:	735113	Length:	763	Species:	Rattus norvegicus

Alignment Length:	384	Identity:	62/384 - (16%)
Similarity:	123/384 - (32%)	Gaps:	135/384 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 KQLRKLAFNGVPDVQSFRALSWKLLLGYLGPRRSSWTTTLAQKRALYKQFIEELVLPPGHSSNRA 89
            ::||.|...|:|  ...|...|..|.|.|..:::|        ...|::.::       :|||..
  Rat   118 EKLRSLVLAGIP--HGMRPQLWMRLSGALQKKKNS--------ELSYREIVK-------NSSNDE 165

  Fly    90 SVDGGDGDKVDSGGVGLQDHPLSEGPESAWNTFFNDNEFLLQIDKDVRRLCPDISFFQQPTDYPC 154
            ::..                                    .||:||:.|..|..:.|
  Rat   166 TIAA------------------------------------KQIEKDLLRTMPSNACF-------- 186

  Fly   155 EIVVHSKGEHGRRLHERVVPAVLSSANVERKGLGMTKINLITKRSVENYAAMEEGQEAHWEVVQR 219
                                     |||  ..:|:.::                         :|
  Rat   187 -------------------------ANV--NSIGVPRL-------------------------RR 199

  Fly   220 ILFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDLTYRAHAEADCFFCFTALMSEI--RDFFIKT 282
            :|...|.|.|..||.||...:...:...:           .|.|.|:...|::.::  ..:|..|
  Rat   200 VLRALAWLYPEIGYCQGTGMVAACLLLFL-----------EEEDAFWMMCAIIEDLLPASYFSTT 253

  Fly   283 LDDAEGGIKFMMARLSNMLKSKDLSIYELLRSQELHPQYYSFRWLTLLLSQEFPLPDVLRIWDSV 347
            |...:...:.:...:...|...|    :||:..::.....:..|.....:....:..:|||||..
  Rat   254 LLGVQTDQRVLRHLIVQYLPRLD----KLLQEHDIELSLITLHWFLTAFASVVHIRLLLRIWDLF 314

  Fly   348 FADEQRFDFLIKICCSMILIQREAILENDFASNV-KLLQNYPP--IDINVVIAHAGSLA 403
            |.:...  .|.:....|:.::.|.:::::.:::: ..|.:.|.  .|..:::..|..||
  Rat   315 FYEGSL--VLFQTTLGMLRLKEEELIQSENSASIFNTLSDIPAQMDDAELLLGEAMQLA 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	30/183 (16%)
Sgsm3	NP_942082.2	TBC	127..338	CDD:214540	53/340 (16%)
		SH3_SGSM3	497..549	CDD:212747
		RUN	576..727	CDD:397055
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810