DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GAPsec and Tbc1d17

DIOPT Version :9

Sequence 1:	NP_648245.2	Gene:	GAPsec / 38987	FlyBaseID:	FBgn0035916	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001099728.1	Gene:	Tbc1d17 / 292886	RGDID:	1309686	Length:	646	Species:	Rattus norvegicus

Alignment Length:	367	Identity:	79/367 - (21%)
Similarity:	144/367 - (39%)	Gaps:	111/367 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 GPQD-LIDLKQLRKLAFNG--VPDVQSFRALSWKLLLGYLGPRRSSWTTTLAQKRALYKQFIEEL 78
            ||:. |.::.:|:...|:|  .|   ..|..:||.|||||     ||.::..:.:|..::..:|.
  Rat   292 GPEGRLQNVPELKSRIFSGGLSP---GLRREAWKFLLGYL-----SWESSAEEHKAHVRKKTDEY 348

  Fly    79 VLPPGHSSNRASVDGGDGDKVDSGGVGLQDHPLSEGPESAWNTFFNDNEFLLQIDKDVRRLCPDI 143
            .                       .:.||...:|...|.. |:..:....|  |::||.|.....
  Rat   349 F-----------------------RMKLQWKSVSAEQERR-NSLLHGYRSL--IERDVSRTDRTN 387

  Fly   144 SFFQQPTDYPCEIVVHSKGEHGRRLHERVVPAVLSSANVERKGLGMTKINLITKRSVENYAAMEE 208
            .|::.|                                 |..|||:
  Rat   388 KFYEGP---------------------------------ENPGLGL------------------- 400

  Fly   209 GQEAHWEVVQRILFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDLTYRAHAEADCFFCFTALMS 273
                    :..||..|...:...||||||::::.||.:|:.:          |.|.|:||...|.
  Rat   401 --------LNDILLTYCMYHFDLGYVQGMSDLLSPILFVVQN----------EVDAFWCFCGFME 447

  Fly   274 EIRDFFIKTLDDAEGGIKFMMARLSNMLKSKDLSIYELLRSQELHPQYYSFRWLTLLLSQEFPLP 338
            .:...|    ::::..:|..:.:|..:|:..|..:.:.|.||:.....:.||||.:...:|||.|
  Rat   448 LVHGNF----EESQETMKRQLGQLLLLLRVLDQPLCDFLDSQDSGSLCFCFRWLLIWFKREFPFP 508

  Fly   339 DVLRIWDSVFADEQRFDFLIKICCSMILIQREAILENDFASN 380
            ||||:|:.::......:..:.:.|:::.::|:.::.:.|.||
  Rat   509 DVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSN 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	41/181 (23%)
Tbc1d17	NP_001099728.1	DUF3548	3..218	CDD:192931
Tbc1d17	NP_001099728.1	TBC	308..543	CDD:214540	72/342 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810