Protein Alignment GAPsec and Tbc1d12

DIOPT Version :9

• Sequence 1: NP_648245.2
• Gene: GAPsec / 38987
• FlyBaseID: FBgn0035916
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_666064.3
• Gene: Tbc1d12 / 209478
• MGIID: 2384803
• Length: 698
• Species: Mus musculus
• Alignment Length: 398
• Identity: 79/398 - (19%)
• Similarity: 128/398 - (32%)
• Gaps: 133/398 - (33%)

  Fly     2 SIFKARVKEFEDVLAGPQDLIDLKQLRKLAFNGVPDVQSFRALSWKLLLG-YLGPRRSSWTTTLA 65
            ||..|.|....::|...:.:...:::|:|.:.|:|  .|.|...|.|.:| .|......:...|:
Mouse   375 SIASAMVIWINEILPNWEVMRSTRRVRELWWQGLP--PSVRGKVWSLAVGNELNITPELYEIFLS 437

  Fly    66 QKRALYKQFIEELVLPPGHSSNRASVDGGDGDKVDSGGVGLQDHPLSEGPESAWNTFFNDNEFLL 130
            :.:..:|.|.|      ..|.|            |:.|:.:.|...|                |.
Mouse   438 RAKERWKSFSE------SSSEN------------DTEGLSVADREAS----------------LE 468

  Fly   131 QIDKDVRRLCPDISFFQQPTDYPCEIVVHSKGEHGRRLHERVVPAVLSSANVERKGLGMTKINLI 195
            .|..|:.|..|.:..||:...|
Mouse   469 LIKLDISRTFPSLYIFQKGGPY------------------------------------------- 490

  Fly   196 TKRSVENYAAMEEGQEAHWEVVQRILFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDLTYRAHA 260
                             | :|:..||..|....|..||||||:.|...:...:           .
Mouse   491 -----------------H-DVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNL-----------E 526

  Fly   261 EADCFFCFTALMSEIRDFFIKTLDDAEGGIKFMMARLSNMLK---------SKDLS-IYELLRSQ 315
            |||.|..|..|:::            ...:.|.....|.|||         .::|| ::...:|.
Mouse   527 EADAFIAFANLLNK------------PCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSY 579

  Fly   316 ELHPQYYSFRWLTLLLSQEFPLPDVLRIWDSVFADEQRFDFLIKICCSMILIQREAILENDFASN 380
            .|.|..|...|:..|.|:..||....|:||....|.:  :||.:....::.:..:.:|:.||...
Mouse   580 NLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGE--EFLFRTGLGILRLYEDILLQMDFIHI 642

  Fly   381 VKLLQNYP 388
            .:.|...|
Mouse   643 AQFLTKLP 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	41/191 (21%)
Tbc1d12	NP_666064.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..59
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	93..123
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	158..236
		COG5210	304..639	CDD:227535	75/385 (19%)
		RabGAP-TBC	468..635	CDD:278964	48/252 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810