Protein Alignment GAPsec and tbc-13

DIOPT Version :9

• Sequence 1: NP_648245.2
• Gene: GAPsec / 38987
• FlyBaseID: FBgn0035916
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_001359553.1
• Gene: tbc-13 / 181406
• WormBaseID: WBGene00009726
• Length: 425
• Species: Caenorhabditis elegans
• Alignment Length: 405
• Identity: 182/405 - (44%)
• Similarity: 248/405 - (61%)
• Gaps: 30/405 - (7%)

  Fly     2 SIFKARVKEFEDVLAGPQDLIDLKQLRKLAFNGVPDVQSFRALSWKLLLGYLGPRRSSWTTTLAQ 66
            |.:..|:.:.|:||......||:.:||.....|||  :|.|.|:|:|||.||...|..|.|.||:
 Worm     3 SRYMERLAKIEEVLLIANKKIDINELRAGCSYGVP--ESLRPLAWRLLLHYLPLERHKWQTFLAE 65

  Fly    67 KRALYKQFIEELVLPPGHSSNRASVDGGDGDKVDSGGVGLQDHPLSEGPESAWNTFFNDNEFLLQ 131
            :|..|.|.||::::.||.:|.:.|......:          |||||:.|.|.|..||.||:.|.|
 Worm    66 QRDNYDQMIEQIIVEPGTASLQQSAAQNQDN----------DHPLSDHPTSDWQAFFQDNKVLSQ 120

  Fly   132 IDKDVRRLCPDISFFQQPTDYPCEIVVHSKGEHGRR--LHERVV-PAVLSSA--NVERKGL-GMT 190
            ||||||||.|:|.|||..:.:|     |   :||.:  |..||: ...|.|.  ...|.|: |..
 Worm   121 IDKDVRRLYPEIQFFQLLSRFP-----H---QHGMKYPLSRRVINHQELHSQEFGANRDGIVGCV 177

  Fly   191 KINLITKRSVENYAAMEEGQEAHWEVVQRILFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDLT 255
            |.|:..:...||.|   ...|.||.:|:||||||||||||..|||||||:|.|||||.|:|.|..
 Worm   178 KTNIAKQSQDENQA---PNSEFHWHIVERILFIYAKLNPGVQYVQGMNELVAPIYYVFANDADDE 239

  Fly   256 YRAHAEADCFFCFTALMSEIRDFFIKTLDDAEGGIKFMMARLSNMLKSKDLSIYE-LLRSQELHP 319
            :.|:||||.||||..||||::|.|||.|||:..||:..|:...|::.:.|..::: |..:.|:.|
 Worm   240 WAAYAEADTFFCFQQLMSEVKDNFIKKLDDSNCGIESSMSAFHNLISTFDTELHKHLTLTLEIKP 304

  Fly   320 QYYSFRWLTLLLSQEFPLPDVLRIWDSVFADEQRFDFLIKICCSMILIQREAILENDFASNVKLL 384
            |:|:||||:||||||||||||:.:||::|:|.|||..|..:|.:|:.::||.::..||...|:||
 Worm   305 QFYAFRWLSLLLSQEFPLPDVITLWDALFSDPQRFALLQYVCLAMMELKREPLINGDFPFCVRLL 369

  Fly   385 QNYPPIDINVVIAHA 399
            ||||..||..::|.|
 Worm   370 QNYPDTDIAKIVAFA 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	95/182 (52%)
tbc-13	NP_001359553.1	TBC	32..358	CDD:214540	160/348 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166917
Domainoid	1	1.000	183	1.000	Domainoid score	I2044
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10068
Inparanoid	1	1.050	317	1.000	Inparanoid score	I1519
Isobase	1	0.950	-	0	Normalized mean entropy	S2189
OMA	1	1.010	-	-		QHG54276
OrthoDB	1	1.010	-	-		D350831at33208
OrthoFinder	1	1.000	-	-		FOG0001234
OrthoInspector	1	1.000	-	-		oto19839
orthoMCL	1	0.900	-	-		OOG6_102218
Panther	1	1.100	-	-	LDO	PTHR22957
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1952
SonicParanoid	1	1.000	-	-		X4286
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	17.750