DRSC/TRiP Functional Genomics Resources

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Protein Alignment GAPsec and tbc-2

DIOPT Version :9

Sequence 1:NP_648245.2 Gene:GAPsec / 38987 FlyBaseID:FBgn0035916 Length:403 Species:Drosophila melanogaster
Sequence 2:NP_495156.1 Gene:tbc-2 / 173986 WormBaseID:WBGene00022880 Length:908 Species:Caenorhabditis elegans


Alignment Length:356 Identity:60/356 - (16%)
Similarity:109/356 - (30%) Gaps:136/356 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 VLAGPQDLIDLKQLRKLAFNGVPDVQSFRALSWKLLLGYLGPRRSSWTTTLAQKRA-LYKQFIEE 77
            :::.|    |||.|.:   .|||  .::|...||:::       :.|   :..|:| |...:.:.
 Worm   617 IMSSP----DLKTLIR---TGVP--PAYRGRVWKIIV-------THW---VKDKQAELGNGYYQS 662

  Fly    78 LVLPPGHSSNRASVDGGDGDKVDSGGVGLQDHPLSEGPESAWNTFFNDNEFLLQIDKDVRRLCPD 142
            ::...|......|.|..                                  :.|||.|:.|..|.
 Worm   663 MLRKAGTKKQDGSYDAA----------------------------------IKQIDLDLARTLPT 693

  Fly   143 ISFFQQPTDYPCEIVVHSKGEHGRRLHERVVPAVLSSANVERKGLGMTKINLITKRSVENYAAME 207
            ...|.:|                            .|||:|:                       
 Worm   694 NKLFDEP----------------------------DSANIEK----------------------- 707

  Fly   208 EGQEAHWEVVQRILFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDLTYRAHAEADCFFCFTALM 272
                     ::.:|:.:...|...||.||:|.:..    :...:.|       |.|.|:...|.:
 Worm   708 ---------LRNVLYAFRYHNSHVGYCQGLNRLAA----IALLNLD-------EQDSFWFLVACV 752

  Fly   273 SEIR--DFFIKTLDDAEGGIKFMMARLSNMLKSKDLSIYELLRSQELHPQYYSFRWLTLLLSQEF 335
            ..::  .::..:|..|....|.    |.:::..|...:...||:.|:....::..|.........
 Worm   753 EHLQPEGYYTSSLIGAVADQKV----LRDLVAEKLPKLAAHLRALEVDLSLFALSWFLTCFVDVL 813

  Fly   336 PLPDVLRIWDSVFADEQRFDF-----LIKIC 361
            |....|.|:|:...:..:..|     |.|||
 Worm   814 PHSIYLTIFDAFLYEGNKVLFRFALALFKIC 844

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GAPsecNP_648245.2 TBC <191..373 CDD:214540 30/178 (17%)
tbc-2NP_495156.1 PH_TBC1D2A 20..119 CDD:269966
PH 20..111 CDD:278594
ATG16 235..400 CDD:285778
DUF1664 <289..368 CDD:285172
TBC 627..849 CDD:214540 55/342 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5210
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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