DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GAPsec and tbck-1

DIOPT Version :9

Sequence 1:	NP_648245.2	Gene:	GAPsec / 38987	FlyBaseID:	FBgn0035916	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001364726.1	Gene:	tbck-1 / 173832	WormBaseID:	WBGene00016352	Length:	839	Species:	Caenorhabditis elegans

Alignment Length:	226	Identity:	41/226 - (18%)
Similarity:	98/226 - (43%)	Gaps:	23/226 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   176 VLSSANVERKGLGMTKINLITKRSVENYAAMEEGQEAHWEVVQRILFIYAKLNPGQGYV--QGMN 238
            ||:|.:.:|:    .::::......::|......||:    ::::|..:..:...|.:|  ||.:
Worm   476 VLASHSSDRQ----LEVDIPRCHQYDSYMTTPAIQES----LRKVLKGWQIVTESQHFVYWQGCD 532

  Fly   239 EIVGPIYYVMASDPDLTYRAHAEADCFFCFTALMSEIRDFFIKTLDDAEGGIKFMMARLSNMLKS 303
            .:..|......|.|.:.:....|....:|        ..|::|  |::| .||..:....:::..
Worm   533 SLATPFLLANMSKPHVAFACFKEFTYRYC--------HKFYLK--DNSE-VIKEYLGIFYHLVAY 586

  Fly   304 KDLSIYELLRSQELHPQYYSFRWLTLLLSQEFPLPDVLRIWDSVFADEQRFDFLIKICCSMILIQ 368
            .|..:|:.|:......:.::..|.....:.|.||..::.:||........|..:|.:  :|:...
Worm   587 TDPVLYKHLKINGFDAELFAIPWFLTCFAHELPLSKLVLLWDETMMHGNAFPLMIAL--AMLNRL 649

  Fly   369 REAILENDFASNVKLLQNYPPIDINVVIAHA 399
            |:.:|..:|...:.::.:.|.:.|:.:|.::
Worm   650 RDKLLAVNFNEMIIIIHDQPDLSIDEIIKNS 680

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	32/183 (17%)
tbck-1	NP_001364726.1	PKc_like	<42..238	CDD:419665
tbck-1	NP_001364726.1	TBC	444..654	CDD:214540	36/198 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910