Protein Alignment GAPsec and TBC1D21

DIOPT Version :9

• Sequence 1: NP_648245.2
• Gene: GAPsec / 38987
• FlyBaseID: FBgn0035916
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: XP_006720472.1
• Gene: TBC1D21 / 161514
• HGNCID: 28536
• Length: 399
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 68/377 - (18%)
• Similarity: 115/377 - (30%)
• Gaps: 143/377 - (37%)

  Fly    42 RALSWKLLLGYLGPRRSSW-------TTTLAQKRALYK---QFIEELVLPPGHSSNRASVDGGDG 96
            |..:||.|.||.     ||       .|..:.:|..||   |..|::
Human    63 RTEAWKFLTGYF-----SWQSSQDERLTVDSMRRKNYKALCQMYEKI------------------ 104

  Fly    97 DKVDSGGVGLQDHPLSEGPESAWNTFFNDNEFLLQIDKDVRRLCPDISFFQQPTDYPCEIVVHSK 161
                        .||.|      |...|..|....|.:|:::                   ::.|
Human   105 ------------QPLLE------NLHRNFTETRNNIARDIQK-------------------IYDK 132

  Fly   162 GEHGRRLHERVVPAVLSSANVERKGLGMTKINLITKRSVENYAAMEEGQEAHWEVVQRILFIYAK 226
            ...|               ||           ||.|:.:|                 :||.:...
Human   133 DPLG---------------NV-----------LIDKKRLE-----------------KILLLSYV 154

  Fly   227 LNPGQGYVQGMNEIVGPIYYVMASDPDLTYRAHAEADCFFCFTALMSEIRDFFI------KTLDD 285
            .|....|.||.:|:: .::.:|...         :.:.|:.|...:.:.....:      |.||.
Human   155 CNTQAEYQQGFHEMM-MLFQLMVEH---------DHETFWLFQFFLQKTEHSCVINIGVAKNLDM 209

  Fly   286 AEGGIKFMMARLSNMLKSKDLSIYELLRSQELHPQYYSFRWLTLLLSQEF-PLPDVLRIWDSVFA 349
            ....|.|:....:..||.|.....:.|           |.|......:.| ...||.|:|:.:..
Human   210 LSTLITFLDPVFAEHLKGKGAGAVQSL-----------FPWFCFCFQRAFKSFDDVWRLWEVLLT 263

  Fly   350 DEQRFDFLIKICCSMILIQREAILENDFASNVKLL--QNYPPIDINVVIAHA 399
            .:...:|.:.:..||:.:.||.:|:.....:..||  .|...:|.:.:|:.|
Human   264 GKPCRNFQVLVAYSMLQMVREQVLQESMGGDDILLACNNLIDLDADELISAA 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	35/188 (19%)
TBC1D21	XP_006720472.1	TBC	62..287	CDD:214540	61/347 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810