Protein Alignment GAPsec and TBC1D16

DIOPT Version :9

• Sequence 1: NP_648245.2
• Gene: GAPsec / 38987
• FlyBaseID: FBgn0035916
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: XP_024306344.1
• Gene: TBC1D16 / 125058
• HGNCID: 28356
• Length: 824
• Species: Homo sapiens
• Alignment Length: 435
• Identity: 104/435 - (23%)
• Similarity: 152/435 - (34%)
• Gaps: 176/435 - (40%)

  Fly    26 QLRKLAFNGVPDVQSFRALSWKLLLGYLGPRRSSWTTTLAQKRALYKQFIEELVLPPGHSSNRAS 90
            :|||..|.|..|| |.|...|..||.|.     |..:|..::.||..|..:|      :|.
Human   416 KLRKAIFFGGIDV-SIRGEVWPFLLRYY-----SHESTSEEREALRLQKRKE------YSE---- 464

  Fly    91 VDGGDGDKVDSGGVGLQDHPLSEGPESAWNTFFNDNEFLLQIDKDVRRLCPDISFFQQPTDYPCE 155
                           :|...||..||. ...|:.:.:|  .:||||.|...:..||
Human   465 ---------------IQQKRLSMTPEE-HRAFWRNVQF--TVDKDVVRTDRNNQFF--------- 502

  Fly   156 IVVHSKGEHGRRLHERVVPAVLSSANVERKGLGMTKINLITKRSVENYAAMEEGQEAHWEVVQRI 220
                 :||              .:.|||.                                ::||
Human   503 -----RGE--------------DNPNVES--------------------------------MRRI 516

  Fly   221 LFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDLTYRAHAEADCFFCFTALM------SEIRDFF 279
            |..||..||..||.|||:::|.||   :|...|       |:|.|:||..||      |..||..
Human   517 LLNYAVYNPAVGYSQGMSDLVAPI---LAEVLD-------ESDTFWCFVGLMQNTIFVSSPRDED 571

  Fly   280 I-KTLDD-----------------AEGGIKFMMAR-------------LSNMLKS-----KDLSI 308
            : |.|::                 ..|....::.|             .|..::|     :.|.:
Human   572 MEKQLEEWTWETAPKCALRVGSLPGHGAAASVLPRPGTTLCLTLDHTTASGTVRSGRNWQRQLYL 636

  Fly   309 YELLRSQELHPQYYS---------------FRWLTLLLSQEFPLPDVLRIWDSVFADEQRFDFLI 358
            .||||.  .|.::|.               .|||.|...:|||..:.||||::.:|..|...|.:
Human   637 RELLRL--THVRFYQHLVSLGEDGLQMLFCHRWLLLCFKREFPEAEALRIWEACWAHYQTDYFHL 699

  Fly   359 KICCSMILIQREAILENDFASNVKLLQNYPPIDINVVIAHAGSLA 403
            .||.:::.|..:.::|...|::..||             |.|:||
Human   700 FICVAIVAIYGDDVIEQQLATDQMLL-------------HFGNLA 731

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	57/238 (24%)
TBC1D16	XP_024306344.1	TBC	424..709	CDD:214540	91/390 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810