Protein Alignment GAPsec and Tbc1d14

DIOPT Version :9

• Sequence 1: NP_648245.2
• Gene: GAPsec / 38987
• FlyBaseID: FBgn0035916
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_001106833.1
• Gene: Tbc1d14 / 100855
• MGIID: 1098708
• Length: 714
• Species: Mus musculus
• Alignment Length: 423
• Identity: 88/423 - (20%)
• Similarity: 140/423 - (33%)
• Gaps: 83/423 - (19%)

  Fly     5 KARVKEFEDVLAGPQDLIDLKQ-LRKLAFNGVPDVQSFRALSWKLLLGYLGPRRSSWTTTLAQKR 68
            |...||:||....|......|| :||..        .|..||...|:  |..|.::.....|::.
Mouse   298 KKTQKEYEDKAGRPSRPPSPKQNVRKNL--------DFEPLSTTALI--LEDRPANLPAKPAEEA 352

  Fly    69 ALYKQFIEELVLPP------------GHSSNRASVDGGDGDKVDSGGVGLQDHPLSEGPESAWNT 121
            ..::|..||:||..            .....|..|:...|:.|                 ..||.
Mouse   353 QKHRQQYEEMVLQAKKRELKEAQRRRKQLEERCKVEESIGNAV-----------------LTWNN 400

  Fly   122 FFNDNEFLLQIDKDVRRLCPDISFFQQPTDYPCEIVVHSKGEHGRRLH-----------ERVVPA 175
            ....|...:...|.||    |:.:...|.....::...:.|......|           ||....
Mouse   401 EILPNWETMWCSKKVR----DLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRSL 461

  Fly   176 VLSSANVERKGLGMTK---------INLITKRSVENYAAMEEGQEAHWEVVQRILFIYAKLNPGQ 231
            ....:.||.:..|.:.         |.|...|:..|....::|...| :::..||..|....|..
Mouse   462 STGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQGGPYH-DMLHSILGAYTCYRPDV 525

  Fly   232 GYVQGMNEIVGPIYYVMASDPDLTYRAHAEADCFFCFTALMSEIRDFFIKTLDDAEGGIKFMMAR 296
            ||||||:.|..    |:..:.|       .||.|..|:.|:::........:|  .|.:....|.
Mouse   526 GYVQGMSFIAA----VLILNLD-------TADAFIAFSNLLNKPCQMAFFRVD--HGLMLTYFAA 577

  Fly   297 LSNMLKSKDLSIYELLRSQELHPQYYSFRWLTLLLSQEFPLPDVLRIWDSVFADEQRFDFLIKIC 361
            .....:.....::...:...|....|...|:..|.|:..||....||||....|.:  :||.:..
Mouse   578 FEVFFEENLPKLFAHFKKNNLTADIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGE--EFLFRTA 640

  Fly   362 CSMILIQREAILENDFASNVKLLQNYP---PID 391
            ..::.:..:.:...||..:.:.|...|   |.|
Mouse   641 LGILKLFEDILTRMDFIHSAQFLTRLPEDLPAD 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	41/190 (22%)
Tbc1d14	NP_001106833.1	ARGLU	<350..>392	CDD:373772	7/41 (17%)
		TBC	419..651	CDD:214540	49/247 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900