DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GAPsec and tbc1d9b

DIOPT Version :9

Sequence 1:	NP_648245.2	Gene:	GAPsec / 38987	FlyBaseID:	FBgn0035916	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	XP_009305930.1	Gene:	tbc1d9b / 100332046	-ID:	-	Length:	1218	Species:	Danio rerio

Alignment Length:	285	Identity:	62/285 - (21%)
Similarity:	97/285 - (34%)	Gaps:	93/285 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 EIVVHSKGEHGRRLHERVVPAVLSSANVERKGLGMTKINLITKRSVENYAAMEEGQEAHWEVVQR 219
            |:..| .|.:|..:.:.:....|::..:||.          ..||:..:.|.:  .|.....::|
Zfish   515 EMATH-PGYYGNLVEQAMGRCTLATEEIERD----------LHRSMPEHHAFQ--NETGIAALRR 566

  Fly   220 ILFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDLTYRAHAEADCFFCFTALMSEIRDFFIKTLD 284
            :|..||..|||.||.|.||.:...:         |.|....||  |:...||...:...:..|
Zfish   567 VLTAYAYRNPGIGYCQAMNIVTSVL---------LLYCTEEEA--FWLLVALCERMLPDYYNT-- 618

  Fly   285 DAEGGIKFMMARLSNMLKSKDLSIYELLRSQELHPQYY------------SFRW-LTLLLSQEFP 336
                       |:...|  .|..::|.| ::|..|..|            |..| |||.|| ..|
Zfish   619 -----------RVVGAL--VDQGVFEEL-TRECLPLLYEHMQDLGVISTISLSWFLTLFLS-VMP 668

  Fly   337 LPDVLRIWDSVFADEQRFDFLIKIC-----------CS-----MILIQREAILENDFASNVKLLQ 385
            ....:.:.|..|.:..:..|.:.:.           ||     |.::.|       :..||...|
Zfish   669 FDSAVLLVDCFFYEGIKVIFQVSLAVLHANMDQLLSCSDEGEAMTILGR-------YLDNVVNKQ 726

  Fly   386 ----------------NYPPIDINV 394
                            |.||.:|:|
Zfish   727 TVSPPIPHLHALLTSGNNPPPEIDV 751

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	47/210 (22%)
tbc1d9b	XP_009305930.1	PH-GRAM1_TCB1D9_TCB1D9B	153..251	CDD:275420
		PH-GRAM2_TCB1D9_TCB1D9B	300..395	CDD:270161
		TBC	493..703	CDD:214540	50/228 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900