DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GAPsec and sgsm1a

DIOPT Version :9

Sequence 1:	NP_648245.2	Gene:	GAPsec / 38987	FlyBaseID:	FBgn0035916	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	XP_009299656.1	Gene:	sgsm1a / 100270734	ZFINID:	ZDB-GENE-060526-379	Length:	1392	Species:	Danio rerio

Alignment Length:	373	Identity:	81/373 - (21%)
Similarity:	143/373 - (38%)	Gaps:	90/373 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 GYLGPRRSSWTTTLAQKRALYKQFIEELVLPPGHS--SNRASVDGGDGDKVDS--GGVGLQDHPL 111
            |..|.|::.     .|::|   ..:||.| |..|.  |||...:..|..:.|.  ..:.:::.|.
Zfish  1037 GPTGKRKAD-----MQRKA---PVVEETV-PLVHEAFSNRKMSEAQDETESDESPSAIEMEEIPT 1092

  Fly   112 SEGPESAWNTFFNDNEFLLQIDKDVRRLCPDISFFQQPTDYPCEIVVHSKGEHGRRLHERVVP-- 174
            ::    .|.                |:..|.....:|.|....|:.:..  .||:...|.|.|
Zfish  1093 AK----VWE----------------RKSSPKRRTTEQATIPALELRLEE--AHGKLSSEEVNPEK 1135

  Fly   175 ------------------AVLSSANVERKG------------LGMTKINLITKRSVENYAAMEEG 209
                              .:.:|:.|...|            |.:.:|:...:|...||...
Zfish  1136 PEMESLCPQLDSLAVNTEKIEASSPVSSIGTTYSQELLDMYTLNLHRIDKDVQRCDRNYWYF--- 1197

  Fly   210 QEAHWEVVQRILFIYAKLNPGQGYVQGMNEIVGPIYYVMASDPDLTYRAHAEADCFFCFTALMSE 274
            ..|:.|.::.|:..|...:...||||||.:::.|:..::..          ||..|.|||.||..
Zfish  1198 TPANLEKLRNIMCSYVWQHLEIGYVQGMCDLLAPLLVILDD----------EAMAFSCFTELMKR 1252

  Fly   275 IRDFFIKTLDDAEGGIKFMMARLSNMLKSKDLSIYELLRSQELHPQ-YYSFRWLTLLLSQEFPLP 338
            :...|     ...|.:....|.:.::::..|..::||:.....:.. |:.:||..|...:|....
Zfish  1253 MNQNF-----PHGGAMDTHFANMRSLIQILDAELFELMHQNGDYTHFYFCYRWFLLDFKRELVYD 1312

  Fly   339 DVLRIWDSVFADE--QRFDFLIKICCSMILIQREAILEN--DFASNVK 382
            ||..:|::::|.:  ....|::.|..|::.|.|:.||||  ||...:|
Zfish  1313 DVFAVWETIWAAKCVSSSHFVLFIALSLVEIYRDIILENNMDFTDIIK 1360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAPsec	NP_648245.2	TBC	<191..373	CDD:214540	43/184 (23%)
sgsm1a	XP_009299656.1	RUN	44..188	CDD:280855
		PH_RUTBC	256..425	CDD:275431
		TBC	1168..1349	CDD:214540	44/198 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910