DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment S-Lap1 and LAP1

DIOPT Version :9

Sequence 1:	NP_648244.1	Gene:	S-Lap1 / 38986	FlyBaseID:	FBgn0035915	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001118375.1	Gene:	LAP1 / 816954	AraportID:	AT2G24200	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	537	Identity:	155/537 - (28%)
Similarity:	249/537 - (46%)	Gaps:	108/537 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 LVIGVYADEED---------------KNDA---GILTPAGWRYNLQKTNGRLIEVLRMSGPMPKR 102
            ||:||  .|:|               |.||   |:|.......:.....|: ..|||:.|...||
plant    35 LVVGV--TEKDLAKDGNSKFENPILSKVDAHLSGLLAQVSSEEDFTGKPGQ-STVLRLPGLGSKR 96

  Fly   103 GEARLLFAVEPERIPYYSVVAVVGLGKECLGYNPYEVLDEQKEAIRR---SVAAACRILAELDTD 164
                               :|::|||:.......:..|.|....:.:   |.:||. :||...:|
plant    97 -------------------IALIGLGQSVSSPVAFHSLGEAVATVSKASQSTSAAI-VLASSVSD 141

  Fly   165 RIEVENCGHAESAAEGAALGIWLYQELRDPKTRIFVPAIDL--YATKDEVCDIEGWRIGLQKAA- 226
            ..::.:   ..:.|.|..||::.....:....:..:.|:|:  :.|..||          :|..
plant   142 ESKLSS---VSALASGIVLGLFEDGRYKSESKKPSLKAVDIIGFGTGAEV----------EKKLK 193

  Fly   227 -AQNLT------RQLQEMPSNLLTPTAFAQNVVEVLCK-SGV-NVEVKVEGWAESQSMHAFLAVG 282
             |::::      |:|...|:|:|||...|:...:|... |.| ...:..|...:...|.::|||.
plant   194 YAEDVSYGVIFGRELINSPANVLTPAVLAEEAAKVASTYSDVFTANILNEEQCKELKMGSYLAVA 258

  Fly   283 KASCEPPIFLELSYYGTCAEERP--------IVLVGQGITYDAGGLCLKK----KKELFNMRGDM 335
            .||..||.|:.|.|       :|        :.|||:|:|:|:||..:|.    ..||  |:.||
plant   259 AASANPPHFIHLVY-------KPPNGSVKTKLALVGKGLTFDSGGYNIKTGPGCSIEL--MKFDM 314

  Fly   336 TGAAVVVATCRAVAGLRLP-VNIRGLIPLCENVVGCNSFRPGDMVKSMNGKTIEVQCTDHEDVLV 399
            .|:|.|:...:|:..::.| |.:..::..|||::.....||||::.:.|||||||..||.|..|.
plant   315 GGSAAVLGAAKAIGEIKPPGVEVHFIVAACENMISGTGMRPGDVITASNGKTIEVNNTDAEGRLT 379

  Fly   400 LADALLYAQNFCPKCIIDIGTCSGYMRQSLDEAACGVFTNSEILWQQIKHASMHTGDRVWRFPLW 464
            |||||:||.|.....|:|:.|.:|....:|..:..|::|.|:.|.:::..||..:|:::||.||.
plant   380 LADALVYACNQGVDKIVDLATLTGACVIALGTSMAGIYTPSDELAKEVIAASERSGEKLWRMPLE 444

  Fly   465 NFYSKAVRAGGRSDVQNYGIGRGGRPCKAAAFLREFV-PCGQWMHIDAT----NVMVTNGIDFEY 524
            ..|.:.::: |.:|:.|.| ||.|....||.||::|| ...||||||..    |....:|..|
plant   445 ESYWEMMKS-GVADMVNTG-GRAGGSITAALFLKQFVSEKVQWMHIDMAGPVWNEKKKSGTGF-- 505

  Fly   525 LRRGMAGRPTRTLIEFI 541
               |:|     ||:|::
plant   506 ---GVA-----TLVEWV 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
S-Lap1	NP_648244.1	PRK00913	44..542	CDD:234863	155/537 (29%)
S-Lap1	NP_648244.1	Peptidase_M17	55..541	CDD:238247	155/535 (29%)
LAP1	NP_001118375.1	PRK00913	20..516	CDD:234863	155/537 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	161	1.000	Domainoid score	I1254
eggNOG	1	0.900	-	-		E1_COG0260
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1544
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D562530at2759
OrthoFinder	1	1.000	-	-		FOG0001058
OrthoInspector	1	1.000	-	-		mtm1057
orthoMCL	1	0.900	-	-		OOG6_100682
Panther	1	1.100	-	-	O	PTHR11963
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X713
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.830