Protein Alignment S-Lap1 and NPEPL1

DIOPT Version :9

• Sequence 1: NP_648244.1
• Gene: S-Lap1 / 38986
• FlyBaseID: FBgn0035915
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_078939.3
• Gene: NPEPL1 / 79716
• HGNCID: 16244
• Length: 523
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 91/302 - (30%)
• Similarity: 139/302 - (46%)
• Gaps: 38/302 - (12%)

  Fly   230 LTRQLQEMPSNLLTPTAFAQNVVEVLCKSGV------NVEVKVEGWAESQSMHAFLAVGKASCEP 288
            |..::.:.|.|.:....|.:.:.:|..:.|:      :.|:|..|:.      ....||||:..|
Human   180 LAARIVDTPCNEMNTDTFLEEINKVGKELGIIPTIIRDEELKTRGFG------GIYGVGKAALHP 238

  Fly   289 PIFLELSYYGTCAEERPIVLVGQGITYDAGGLCLKKKKELFNMRGDMTGAAVVVATCRAVAGLRL 353
            |....||:....|.: .|..||:||.||.|||.:|.|..:..|:.|..|||.|:...||......
Human   239 PALAVLSHTPDGATQ-TIAWVGKGIVYDTGGLSIKGKTTMPGMKRDCGGAAAVLGAFRAAIKQGF 302

  Fly   354 PVNIRGLIPLCENVVGCNSFRPGDMVKSMNGKTIEVQCTDHEDVLVLADALLYA-QNFCPKCIID 417
            ..|:..:..|.||.||.|:.||.|:....:|||:|:..||.|..|||||.:.|| ::.....|:|
Human   303 KDNLHAVFCLAENSVGPNATRPDDIHLLYSGKTVEINNTDAEGRLVLADGVSYACKDLGADIILD 367

  Fly   418 IGTCSGYMRQSLDEAACGVFTNSEILWQQ--IKHASMHTGDRVWRFPL-------WNFYSKAVRA 473
            :.|.:|....:..:....|.||| ..|:.  :| |....||.|  .||       ::.::.||
Human   368 MATLTGAQGIATGKYHAAVLTNS-AEWEAACVK-AGRKCGDLV--HPLVYCPELHFSEFTSAV-- 426

  Fly   474 GGRSDVQNYGIGRGGRPCKAAA-FLREFV----PCGQWMHID 510
               :|::|....|...|...|. |:...:    | |.|:|:|
Human   427 ---ADMKNSVADRDNSPSSCAGLFIASHIGFDWP-GVWVHLD 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S-Lap1	NP_648244.1	PRK00913	44..542	CDD:234863	91/302 (30%)
		Peptidase_M17	55..541	CDD:238247	91/302 (30%)
NPEPL1	NP_078939.3	Peptidase_M17	35..487	CDD:238247	91/302 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D562530at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1683
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850