Protein Alignment S-Lap1 and NPEPL1

DIOPT Version :10

• Sequence 1: NP_648244.1
• Gene: S-Lap1 / 38986
• FlyBaseID: FBgn0035915
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_078939.3
• Gene: NPEPL1 / 79716
• HGNCID: 16244
• Length: 523
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 91/302 - (30%)
• Similarity: 139/302 - (46%)
• Gaps: 38/302 - (12%)

  Fly   230 LTRQLQEMPSNLLTPTAFAQNVVEVLCKSGV------NVEVKVEGWAESQSMHAFLAVGKASCEP 288
            |..::.:.|.|.:....|.:.:.:|..:.|:      :.|:|..|:.      ....||||:..|
Human   180 LAARIVDTPCNEMNTDTFLEEINKVGKELGIIPTIIRDEELKTRGFG------GIYGVGKAALHP 238

  Fly   289 PIFLELSYYGTCAEERPIVLVGQGITYDAGGLCLKKKKELFNMRGDMTGAAVVVATCRAVAGLRL 353
            |....||:....|.: .|..||:||.||.|||.:|.|..:..|:.|..|||.|:...||......
Human   239 PALAVLSHTPDGATQ-TIAWVGKGIVYDTGGLSIKGKTTMPGMKRDCGGAAAVLGAFRAAIKQGF 302

  Fly   354 PVNIRGLIPLCENVVGCNSFRPGDMVKSMNGKTIEVQCTDHEDVLVLADALLYA-QNFCPKCIID 417
            ..|:..:..|.||.||.|:.||.|:....:|||:|:..||.|..|||||.:.|| ::.....|:|
Human   303 KDNLHAVFCLAENSVGPNATRPDDIHLLYSGKTVEINNTDAEGRLVLADGVSYACKDLGADIILD 367

  Fly   418 IGTCSGYMRQSLDEAACGVFTNSEILWQQ--IKHASMHTGDRVWRFPL-------WNFYSKAVRA 473
            :.|.:|....:..:....|.||| ..|:.  :| |....||.|  .||       ::.::.||
Human   368 MATLTGAQGIATGKYHAAVLTNS-AEWEAACVK-AGRKCGDLV--HPLVYCPELHFSEFTSAV-- 426

  Fly   474 GGRSDVQNYGIGRGGRPCKAAA-FLREFV----PCGQWMHID 510
               :|::|....|...|...|. |:...:    | |.|:|:|
Human   427 ---ADMKNSVADRDNSPSSCAGLFIASHIGFDWP-GVWVHLD 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S-Lap1	NP_648244.1	Peptidase_M17_N	57..192	CDD:426984
		Peptidase_M17	230..536	CDD:459978	91/302 (30%)
NPEPL1	NP_078939.3	Peptidase_M17	35..487	CDD:238247	91/302 (30%)