Protein Alignment S-Lap1 and lap3

DIOPT Version :9

• Sequence 1: NP_648244.1
• Gene: S-Lap1 / 38986
• FlyBaseID: FBgn0035915
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001108319.1
• Gene: lap3 / 562854
• ZFINID: ZDB-GENE-060719-1
• Length: 517
• Species: Danio rerio
• Alignment Length: 493
• Identity: 217/493 - (44%)
• Similarity: 300/493 - (60%)
• Gaps: 17/493 - (3%)

  Fly    54 RALVIGVYADEEDKNDAGILTPAGWRYNLQKTNGRLIEVLRMSGPMPKRGEARLLFAVEPERIPY 118
            :.||:|||..:.| :|...||.|...:: :..:|||.|:|.:|||..|:|::|:.:.:..:
Zfish    32 KGLVLGVYEQQSD-SDGVSLTEAAAAFD-RSLSGRLSEMLSLSGPPLKKGKSRIFYGLHQD---- 90

  Fly   119 YSVVAVVGLGKECLGYNPYEVLDEQKEAIRRSVAAACRILAELDTDRIEVENCGHAESAAEGAAL 183
            :..|.||||||...|....|..|..||.||.:|:|.||.|.:|:...:||:.||..:||||||.|
Zfish    91 FPSVVVVGLGKSDPGVCGKENWDNCKENIRAAVSAGCRQLQDLEVALVEVDPCGDDQSAAEGAVL 155

  Fly   184 GIWLYQELRDPKTRIFVPAIDLYATKDEVCDIEGWRIGLQKAAAQNLTRQLQEMPSNLLTPTAFA 248
            |::.|.||:..|      .:.:........|...|:.|:.....|||.|||.|.|:|.:|||.||
Zfish   156 GLFEYDELKTKK------KVHVKTRPHGSVDAAAWQKGVLYGDGQNLARQLMEAPANHVTPTVFA 214

  Fly   249 QNVVEVLC--KSGVNVEVKVEGWAESQSMHAFLAVGKASCEPPIFLELSYYGTC-AEERPIVLVG 310
            ..:.:.|.  ...|.|..:.:.|.|.:.|.|||:|.|.|.|||:||||.|.|:. :.:.|:||||
Zfish   215 NTIEQKLSLFADRVIVHKRPQSWIEGEQMGAFLSVSKGSEEPPVFLELHYKGSSDSAQPPLVLVG 279

  Fly   311 QGITYDAGGLCLKKKKELFNMRGDMTGAAVVVATCRAVAGLRLPVNIRGLIPLCENVVGCNSFRP 375
            :|||:|:||:.||....:..||.||.|||.|.:.....|.|::|:||.||.|||||:....:.:|
Zfish   280 KGITFDSGGISLKPSSGMDAMRADMGGAATVCSAIVTAAALKIPINIIGLAPLCENMPSGKANKP 344

  Fly   376 GDMVKSMNGKTIEVQCTDHEDVLVLADALLYAQNFCPKCIIDIGTCSGYMRQSLDEAACGVFTNS 440
            ||:|::.|||||::..||.|..|:|||||.||.:|.|:.||:..|.:|.|..:|..||.||||||
Zfish   345 GDVVRAKNGKTIQIDNTDAEGRLILADALCYAHSFKPRAIINAATLTGAMDVALGSAATGVFTNS 409

  Fly   441 EILWQQIKHASMHTGDRVWRFPLWNFYSKAVRAGGRSDVQNYG-IGRGGRPCKAAAFLREFVPCG 504
            :.||:::..||:.|||||||.||:..|:|.|.....:|:.|.| ..|.|..|.|||||:|||...
Zfish   410 DWLWERLHKASVVTGDRVWRMPLFQHYTKQVTDSALADLNNVGKYSRSGGACTAAAFLKEFVSAN 474

  Fly   505 QWMHIDATNVMVTNGIDFEYLRRGMAGRPTRTLIEFIA 542
            .|.|:|...|| ||..:..|||:||:|||||||:||||
Zfish   475 HWAHLDIAGVM-TNKDEVPYLRKGMSGRPTRTLVEFIA 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S-Lap1	NP_648244.1	PRK00913	44..542	CDD:234863	215/491 (44%)
		Peptidase_M17	55..541	CDD:238247	214/489 (44%)
lap3	NP_001108319.1	Peptidase_M17	32..510	CDD:238247	214/490 (44%)
		PRK00913	34..511	CDD:234863	215/489 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596388
Domainoid	1	1.000	288	1.000	Domainoid score	I1536
eggNOG	1	0.900	-	-		E1_COG0260
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	381	1.000	Inparanoid score	I2017
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D399611at33208
OrthoFinder	1	1.000	-	-		FOG0001058
OrthoInspector	1	1.000	-	-		otm24462
orthoMCL	1	0.900	-	-		OOG6_100682
Panther	1	1.100	-	-	O	PTHR11963
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1683
SonicParanoid	1	1.000	-	-		X713
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.790