Protein Alignment S-Lap1 and lap3

DIOPT Version :10

• Sequence 1: NP_648244.1
• Gene: S-Lap1 / 38986
• FlyBaseID: FBgn0035915
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001011124.1
• Gene: lap3 / 496537
• XenbaseID: XB-GENE-1006711
• Length: 520
• Species: Xenopus tropicalis
• Alignment Length: 502
• Identity: 218/502 - (43%)
• Similarity: 308/502 - (61%)
• Gaps: 23/502 - (4%)

  Fly    54 RALVIGVYADEEDKNDAGILTPAGWRYNLQKTNGRLIEVLRMSGPMPKRGEARLLFAVEPERIPY 118
            :.||:||| ::|.:.::..||.||...: ....|:|.:.|..|||..|:|::|:.:.:..:
 Frog    32 KGLVLGVY-EKEKEEESLTLTNAGDAVD-NAVLGKLRDQLARSGPSLKKGKSRIFYGLHED---- 90

  Fly   119 YSVVAVVGLGKECLGYNPYEVLDEQKEAIRRSVAAACRILAELDTDRIEVENCGHAESAAEGAAL 183
            :..:.||||||:..|.|.:|:.:|.||.||.:|:..||.:.:::..::||:.||.|::|||||.|
 Frog    91 FPSIVVVGLGKKSAGVNQHELWNEAKENIRAAVSVGCRQMQDMEIVQVEVDPCGDAQAAAEGAVL 155

  Fly   184 GIWLYQELRDPKTRIFVPAIDLYATKDEVCDIEGWRIGLQKAAAQNLTRQLQEMPSNLLTPTAFA 248
            |::.|.|::..|.:  .....|:.:.    :|..|..|:..|..|||.|.|.|.|:|.:|||.||
 Frog   156 GLFEYNEMKKKKKK--AVTTHLHGSS----EITAWEKGVLYAEGQNLARHLMEAPANYITPTKFA 214

  Fly   249 QNVVEVLCKSGVNVEV--KVEGWAESQSMHAFLAVGKASCEPPIFLELSYYGTC-AEERPIVLVG 310
            :...:.|...|.||:|  :.:.|.|.|.|.|||:|.|.|.|||:|||:.|.|:. |.:.|:|.||
 Frog   215 ETFEQRLANMGSNVKVFTRSKQWIEEQQMGAFLSVAKGSEEPPVFLEIHYSGSSDASQPPLVFVG 279

  Fly   311 QGITYDAGGLCLKKKKELFNMRGDMTGAAVVVATCRAVAGLRLPVNIRGLIPLCENVVGCNSFRP 375
            :|:|:|:||:.||....:..|||||.|||.|.:.....|.|:||:||..|.|||||:....:.:|
 Frog   280 KGVTFDSGGISLKPSSGMDAMRGDMGGAATVCSAITTAAKLKLPINIISLAPLCENMPNGRANKP 344

  Fly   376 GDMVKSMNGKTIEVQCTDHEDVLVLADALLYAQNFCPKCIIDIGTCSGYMRQSLDEAACGVFTNS 440
            ||:||:.|||||:|..||.|..|:|||||.||.:|.|:.|::..|.:|.|..:|..||.||||||
 Frog   345 GDVVKAKNGKTIQVDNTDAEGRLLLADALCYAHSFNPRAIVNAATLTGAMDVALGSAAAGVFTNS 409

  Fly   441 EILWQQIKHASMHTGDRVWRFPLWNFYSKAVRAGGRSDVQNYG-IGRGGRPCKAAAFLREFVPCG 504
            ..||..::.||:.|||||||.||:..|||.|.....:|:.|.| ..|.|..|.|||||:|||...
 Frog   410 SWLWTHLQEASVVTGDRVWRMPLFEHYSKQVTESALADLNNIGKYSRSGGACTAAAFLKEFVTAP 474

  Fly   505 QWMHIDATNVMVTNGIDFEYLRRGMAGRPTRTLIEFIA------QTI 545
            .|.|:|...|| :|..:..|||:||:||||||||||.|      |||
 Frog   475 HWAHLDIAGVM-SNKDEVPYLRKGMSGRPTRTLIEFAARLSEDKQTI 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S-Lap1	NP_648244.1	Peptidase_M17_N	57..192	CDD:426984	49/134 (37%)
		Peptidase_M17	230..536	CDD:459978	150/309 (49%)
lap3	NP_001011124.1	Peptidase_M17	32..510	CDD:238247	213/490 (43%)