Protein Alignment USP27X and usp-3

DIOPT Version :9

• Sequence 1: NP_001138545.1
• Gene: USP27X / 389856
• HGNCID: 13486
• Length: 438
• Species: Homo sapiens
• Sequence 2: NP_493434.3
• Gene: usp-3 / 190579
• WormBaseID: WBGene00013506
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 382
• Identity: 112/382 - (29%)
• Similarity: 163/382 - (42%)
• Gaps: 87/382 - (22%)

Human    70 TSSFTIGL--RGLINLGNTCFMNCIVQALTHTPILRDF------------------------FLS 108
            |||..|..  ||:.|:|||||||.::|||......|::                        :|:
 Worm   219 TSSSEIAYRPRGMRNVGNTCFMNAVLQALASISEFREYIMSLSSLEDYIHDEKEPKNGGNYCYLT 283

Human   109 DRHRCEMPSPELCLVCEMSSLFRELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAAL 173
            |.:|       ..|:.:.:..|||       |..|.:.............|:||.|:|||:...:
 Worm   284 DEYR-------KLLISQSARSFRE-------PTAPNEFREAFISVCPRFRGFRQHDSHEFMRYFM 334

Human   174 DVLH---RHCKGDDVGKAANNPNHCNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPG 235
            |.||   |.|:     |....|:..:..|.:.|.|.|||.|.||.|...|..||...|:|||:|.
 Worm   335 DSLHTEMRKCR-----KLPGMPDDKHTPISKYFEGTLQSSVICQTCRNCSNKIDEFMDLSLDIPA 394

Human   236 SCTSFWPMSPGRESSVNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMN 300
            .          |.:|.         ..|:|||..|.:.|.|....|.:|..|::.|..:||:.:.
 Worm   395 Q----------RNASK---------VRLSDCLSTFFKLEMLEKGEKPECAKCKTKQTCSKQMFIR 440

Human   301 KLPVVACFHFKRFEHSAKQRRKITTYISFPL-ELDMTPFMASSKESRMNGQLQLPTNSGNNENKY 364
            |||.|.|.|.|||..:..:...|   |.||: :||:|.|:....:       :.|..       |
 Worm   441 KLPQVLCLHMKRFRDNGGKNDAI---IDFPMGQLDVTQFLTDDSD-------EAPCT-------Y 488

Human   365 SLFAVVNHQG-TLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFYHK 420
            ||.:::.|.| ...||||.:|.:.: .:||:.||.|:.......|...:.|:|.|.|
 Worm   489 SLQSIIVHIGYGCGSGHYIAFGKRN-GRWFQFDDTVVKGVDEAHVSKQKAYVLLYTK 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
USP27X	NP_001138545.1	Peptidase_C19D	78..419	CDD:239125	106/369 (29%)
usp-3	NP_493434.3	zf-UBP	53..111	CDD:366940
		UCH	229..542	CDD:366104	106/368 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1867
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D929408at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1591
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.850