DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5989 and LETM2

DIOPT Version :9

Sequence 1:	NP_648242.1	Gene:	CG5989 / 38984	FlyBaseID:	FBgn0017429	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	NP_001319327.1	Gene:	LETM2 / 842865	AraportID:	AT1G65540	Length:	736	Species:	Arabidopsis thaliana

Alignment Length:	453	Identity:	88/453 - (19%)
Similarity:	172/453 - (37%)	Gaps:	96/453 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 RRRLLHLCSSASDKRPTAFC--------SRNY-----ATKPEAAV------------PPQIKRNV 61
            |||...:..|.|:..||..|        .|.|     ..|.|::|            .|.....|
plant     8 RRRSYDVVKSLSEHLPTVQCFSSIERQGQRGYRDFKDVKKKESSVLMEGFYRSRLLQSPSFSNGV 72

  Fly    62 AAEITSVGKVIYETGW------------DANKPIEKPKVRPSSSSSTQPTPSKKPEDEKRKELDT 114
                 .:.::.|..|:            .||||....|....:|.:.:.:|.:..|..:...|..
plant    73 -----GILELPYPLGYRLVFQSMYSSLATANKPDHDKKGEKVTSQTKEASPEECDEAVEGLSLAK 132

  Fly   115 VKSKRDQMRDNMQDYIF----TRYF-----------------NYVKNYDKVLEKNFPKAMQLYRV 158
            .|:|..::.::.:..|.    .|.|                 ::.|.. :..:..|...:|.|.:
plant   133 AKAKAMKLEESQKSDISIMQRVRLFLLGIGPALRAIASMSREDWAKKL-RHWKDEFKSTLQHYWL 196

  Fly   159 FFDGVKDFFGDMKRFLK-IARIANDSPQGIRALNRQELELYMQMPRDMMKVAPALIGCSLPMVGY 222
               |.|..:.|::..:: :.::||.     :.|:|:|.:...:...|:.::.|..:...:|.:.:
plant   197 ---GTKLLWADVRISVRLLVKLANG-----KGLSRRERQQLTRTTADIFRLVPVAVFIIVPFMEF 253

  Fly   223 AFFPLVFYYPRSFLTAHFWTPQQRSEFQSYYMKRRLCNNKDVFRCLQDKLKATASHPKHSAFADI 287
            .....:..:| :.|.:.|....:..|    .:||||....:..:.|||.:|..|...:.|...:|
plant   254 LLPVFLKLFP-NMLPSTFQDKMKEEE----ALKRRLNARMEYAKFLQDTVKEMAKEVQTSRSGEI 313

  Fly   288 ----------LGQLGSGTHPTPEMLIDVKDIFAEGPYSLLGMSRKHVRNLVNLHGLP---SSIFK 339
                      :.::..|...:.:.::....:|.: ..:|..::|..:.|:....|:.   :..:.
plant   314 KKTAEDLDGFMTKVRRGVGVSNDEILGFAKLFND-ELTLDNINRSRLVNMCKYMGISPFGTDAYL 377

  Fly   340 RHRLHEHAFLVHYMDQAITREGGVHNLTPDALRYSCYLRGLNPDSLSS-EAMIEWLRKWVKVS 401
            |:.|.:....:...|:.|..| ||.:|:...||.:|..||:.  .|.| |.|.|.|..|:.:|
plant   378 RYMLRKRLQEIKKDDKLIKAE-GVESLSEAELRQACRERGML--QLGSVEEMREQLVDWLDLS 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5989	NP_648242.1	LETM1	150..403	CDD:285063	55/267 (21%)
LETM2	NP_001319327.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14009
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010