Protein Alignment CG5989 and Letmd1

DIOPT Version :10

• Sequence 1: NP_648242.1
• Gene: CG5989 / 38984
• FlyBaseID: FBgn0017429
• Length: 436
• Species: Drosophila melanogaster
• Sequence 2: NP_598854.1
• Gene: Letmd1 / 68614
• MGIID: 1915864
• Length: 360
• Species: Mus musculus
• Alignment Length: 311
• Identity: 91/311 - (29%)
• Similarity: 154/311 - (49%)
• Gaps: 22/311 - (7%)

  Fly   125 NMQDYIFTRYFNYVKNYDKVLEKNFPKAMQLYRVFFDGVKDFFGDMKRFLKIARIANDS-PQGIR 188
            |:..|:.|:......:|.:.|.::||:...||..|..|::..:.|.|   |..||..|. .|.::
Mouse    55 NLISYVVTKTRAINGSYHRFLGRHFPRFYALYTTFMKGIQMLWADGK---KARRIKADMWKQNLK 116

  Fly   189 --ALNRQELELYMQMPRDMMK-VAPALIGCSLPMVGYAFFPLVFYYPRSFLTAHFWTPQQRSEFQ 250
              .|:.:|:|...|..||:.| :...||... |...|..|.|::.:||..|..|||||:|:.:|.
Mouse   117 FHQLSYREMEHLRQFRRDITKCLFVGLISIP-PFANYLVFLLMYLFPRQLLVKHFWTPKQQIDFL 180

  Fly   251 SYYMKRRLCNNKDVFRCLQDKLKATASHPK-HSAFADILGQLGSGTHPTPEMLIDVKDIFAEGPY 314
            ..|...|..::.:|...|: :.....||.| .....|:..::.|||||..:.::.::|.|:..|
Mouse   181 DVYHGLRRRSHSEVITHLR-RASTFVSHEKLRRQLTDLCTKVQSGTHPAAQDVLALRDCFSTYP- 243

  Fly   315 SLLGMSRKHVRNLVNLHG-------LPSSIFKRHRLHEHAFLVHYMDQAITREGGVHNLTPDALR 372
              ||.|:.....:..|..       ||..:. |.||..|..::|.:|:|:.:. |:..||...::
Mouse   244 --LGFSQLQASQMRALSQAMLLTPYLPPPLL-RQRLKSHTTVIHQLDRALAKL-GIGQLTAQEVK 304

  Fly   373 YSCYLRGLNPDSLSSEAMIEWLRKWVKVSTSIQGEHITLFLHLPILLGYNH 423
            .:|||||||...::.:....||.:|:.:|.|::...::|.||..:||..|:
Mouse   305 SACYLRGLNSTHIADDRCRAWLGEWLHISCSLKEPELSLLLHNVVLLSTNY 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5989	NP_648242.1	LETM1_RBD	190..418	CDD:462258	70/236 (30%)
Letmd1	NP_598854.1	Required and sufficient for mitochondrial import. /evidence=ECO:0000250	1..110		16/57 (28%)
		LETM1_RBD	120..350	CDD:462258	70/236 (30%)