DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5989 and Letmd1

DIOPT Version :9

Sequence 1:	NP_648242.1	Gene:	CG5989 / 38984	FlyBaseID:	FBgn0017429	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	XP_006242416.1	Gene:	Letmd1 / 681352	RGDID:	1596738	Length:	371	Species:	Rattus norvegicus

Alignment Length:	296	Identity:	90/296 - (30%)
Similarity:	147/296 - (49%)	Gaps:	28/296 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 NMQDYIFTRYFNYVKNYDKVLEKNFPKAMQLYRVFFDGVKDFFGDMKRFLKIARIANDS-PQGIR 188
            |:..|:.|:.......|.:.|.::||:...||..|..|::..:.|.|   |..||..|. .|.::
  Rat    55 NLISYVVTKTRAINGTYHRFLGRHFPRFYALYTTFIKGIQMLWADAK---KARRIKADMWKQNLK 116

  Fly   189 --ALNRQELELYMQMPRDMMKVAPALIG-CSL-PMVGYAFFPLVFYYPRSFLTAHFWTPQQRSEF 249
              .|:.:|:|...|..||:.|.  ..|| .|: |...|..|.|::.:||..|..|||||:|:.:|
  Rat   117 FHQLSYREMEHLRQFRRDITKC--LFIGLISIPPFANYLVFLLMYLFPRQLLVKHFWTPKQQIDF 179

  Fly   250 QSYYMKRRLCNNKDVFRCLQDKLKATASHPK---HSAFADILGQLGSGTHPTPEMLIDVKDIFAE 311
            ...|...|..::.::...|: :..|..|:.|   |  ..|:..::.:|||||.:.::.::|.|:.
  Rat   180 LDIYHGFRRRSHLEIITHLR-RASALVSNEKLRWH--LEDLCTKVQNGTHPTAQDILALRDCFST 241

  Fly   312 GPYSLLGMSRKHVRNLVNLHG-------LPSSIFKRHRLHEHAFLVHYMDQAITREGGVHNLTPD 369
            .|   ||.|:.....:..|..       ||..:. |.||..|..::|.:|:|:.:.|..| |||.
  Rat   242 YP---LGFSQLQASQMRALSQAMLLTPYLPPPLL-RWRLKSHTAVIHQLDRALAKLGTGH-LTPQ 301

  Fly   370 ALRYSCYLRGLNPDSLSSEAMIEWLRKWVKVSTSIQ 405
            .:|.:|||||||....|.:....||.:|:.:|.|::
  Rat   302 EVRSACYLRGLNSTHTSDDRCRTWLGEWLHISCSLK 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5989	NP_648242.1	LETM1	150..403	CDD:285063	83/267 (31%)
Letmd1	XP_006242416.1	LETM1	80..337	CDD:285063	84/269 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341728
Domainoid	1	1.000	116	1.000	Domainoid score	I5868
eggNOG	1	0.900	-	-		E1_KOG4263
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9128
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4629
OMA	1	1.010	-	-		QHG49830
OrthoDB	1	1.010	-	-		D330259at33208
OrthoFinder	1	1.000	-	-		FOG0007243
OrthoInspector	1	1.000	-	-		oto96159
orthoMCL	1	0.900	-	-		OOG6_107505
Panther	1	1.100	-	-	LDO	PTHR14009
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5346
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810