DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RpL14 and RPL6

DIOPT Version :9

Sequence 1:	NP_523975.1	Gene:	RpL14 / 38983	FlyBaseID:	FBgn0017579	Length:	166	Species:	Drosophila melanogaster
Sequence 2:	NP_000961.2	Gene:	RPL6 / 6128	HGNCID:	10362	Length:	288	Species:	Homo sapiens

Alignment Length:	141	Identity:	32/141 - (22%)
Similarity:	51/141 - (36%)	Gaps:	42/141 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PFERFVQ-------TGRIAKASAGPLKGRLVAIVDVIDQNRVLVDGPLTGVPRQEYRLNNLHLTK 59
            ||.:.|:       .|.|.....|..:|:.|..:..:....:||.|||.        ||.:.|.:
Human   132 PFSQHVRKLRASITPGTILIILTGRHRGKRVVFLKQLASGLLLVTGPLV--------LNRVPLRR 188

  Fly    60 YRIKFPYTAPTRIVRKAWTESDLKAQWKVSPWSVKAQNICKRSSLND--FDRFKLRYAKRQRNKL 122
            ...||.....|:|        |:             .|:.....|.|  |.:.|||..:.|..::
Human   189 THQKFVIATSTKI--------DI-------------SNVKIPKHLTDAYFKKKKLRKPRHQEGEI 232

  Fly   123 LTIAFNTLKKR 133
                |:|.|::
Human   233 ----FDTEKEK 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpL14	NP_523975.1	KOW_RPL14	7..81	CDD:240512	18/80 (23%)
RpL14	NP_523975.1	Ribosomal_L14e	46..120	CDD:307859	16/75 (21%)
RPL6	NP_000961.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..48
		Ribosomal_L6e_N	36..95	CDD:397788
		KOW_RPL6	136..288	CDD:240520	30/137 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2163
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900