DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nelf-E and nelfe

DIOPT Version :9

Sequence 1:	NP_648241.1	Gene:	Nelf-E / 38982	FlyBaseID:	FBgn0017430	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	XP_021323721.1	Gene:	nelfe / 436648	ZFINID:	ZDB-GENE-040718-69	Length:	378	Species:	Danio rerio

Alignment Length:	359	Identity:	115/359 - (32%)
Similarity:	169/359 - (47%)	Gaps:	101/359 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FPNNLTEEEQMLQAKYQKLKKKKKALQAHKAPKPEPESSLT-LKRP------TDARDAREVARKL 63
            ||::|||:|:.||.||.|||||||||.|.|......::|.| |||.      .|...|.|.|:.|
Zfish    36 FPSSLTEDEEALQKKYAKLKKKKKALMALKKQSSTNQTSQTGLKRTLSDQPVVDTATATEQAKML 100

  Fly    64 IKSGAIPAIQKQTKQDQTSFKRPKGQERAKRSTSETTVASYQPFSSTQNDVAQETIISEIIKEEP 128
            ||||||.||:.:.|  .:.|||.:..|...:...:....::.||   |..|:.:        |||
Zfish   101 IKSGAISAIKSENK--NSGFKRSRMLEGKLKDPEKGPAPAFLPF---QRSVSTD--------EEP 152

  Fly   129 -------RRQNLYQHFA----------------TERDRE-------------------ERGMPEK 151
                   .|::||:.|.                :|||||                   |||...:
Zfish   153 PDSAKRIHRKSLYESFVPGDRSRDEEAGMPSRDSERDREREMDWERDRERDRDRERDRERGRERE 217

  Fly   152 VPMD----------------------------------TAQPEK--PRAGNTIFVSGNKVTEDFL 180
            ...:                                  .:.||:  .|.|||::|.|..:.||.|
Zfish   218 RDRERERDRSRDGERDRERDRDRDRERDRERDGPYRRSDSYPERRGVRKGNTVYVYGTGLVEDSL 282

  Fly   181 KKTFNDYGTIVNVSMEIEKSRGFVSFAKPESADRAIAEIHGKNVNGINLQVQLARRQPQIEPIND 245
            :..|..:|.|:::||:..::..||:|.|.||||:|:||::|..|..:|::|.:||:||.::.
Zfish   283 RTAFAQHGNIIDLSMDSPRNCAFVTFEKIESADQAVAELNGTTVGDVNIKVSIARKQPMLDA--- 344

  Fly   246 ASSSAVWSSIAASKSQKGSHKDHREMVQYDEDFL 279
            |:..:||:|:|...|.|||::|.|..|.|.||||
Zfish   345 ATGKSVWASLAVQNSAKGSYRDKRSQVVYSEDFL 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nelf-E	NP_648241.1	RRM_NELFE	162..236	CDD:240751	30/73 (41%)
nelfe	XP_021323721.1	RRM_NELFE	265..338	CDD:240751	30/72 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I11964
eggNOG	1	0.900	-	-		E1_28IDD
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47031
OrthoDB	1	1.010	-	-		D1377312at2759
OrthoFinder	1	1.000	-	-		FOG0008215
OrthoInspector	1	1.000	-	-		oto40288
orthoMCL	1	0.900	-	-		OOG6_108083
Panther	1	1.100	-	-	LDO	PTHR17250
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4686
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.860