DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nelf-E and Nelfe

DIOPT Version :9

Sequence 1:	NP_648241.1	Gene:	Nelf-E / 38982	FlyBaseID:	FBgn0017430	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_001039328.1	Gene:	Nelfe / 27632	MGIID:	102744	Length:	367	Species:	Mus musculus

Alignment Length:	373	Identity:	107/373 - (28%)
Similarity:	162/373 - (43%)	Gaps:	113/373 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 PNNLTEEEQMLQAKYQKLKKKKKALQA-HKAPKPEPESSLTLKRP------TDARDAREVARKLI 64
            |..|:|||:.||.|:.|||||||||.| .|.....|.|...:||.      .|...|.|.|::|:
Mouse     5 PPGLSEEEEALQKKFNKLKKKKKALLALKKQSSSGPASQGGVKRSLSEQPVVDTATATEQAKQLV 69

  Fly    65 KSGAIPAIQKQTKQDQTSFKRPKGQERAKRSTSETTVASYQPF--SSTQNDVAQETIISEIIKEE 127
            |||||.||:.:||  .:.|||.:..|...:...:..|.::|||  |.:.::..||.      ...
Mouse    70 KSGAISAIKAETK--NSGFKRSRTLEGKLKDPEKGPVPTFQPFQRSMSADEDLQEP------SRR 126

  Fly   128 PRRQNLYQHFATERDR----------------------------EERGM-------PEKVPMDTA 157
            |:|::||:.|.:..||                            ||.|.       |.....|.:
Mouse   127 PQRKSLYESFVSSSDRLRELGQDGEEAEAPGAGDGPPRGFDWSYEEHGSARSSASPPRSRSRDRS 191

  Fly   158 Q--------------------------------------------------------PEK--PRA 164
            .                                                        ||:  ||.
Mouse   192 HDRSRDRDRDKERDRDRDRDRDRDRDKDKDRDRDRDRDRDRDRERDREGPFRRSDSFPERRAPRK 256

  Fly   165 GNTIFVSGNKVTEDFLKKTFNDYGTIVNVSMEIEKSRGFVSFAKPESADRAIAEIHGKNVNGINL 229
            |||::|.|..:|...|:..|:.:|.|:::||:..::..||::.|.||||:|:||::|..|..:.|
Mouse   257 GNTLYVYGEDMTPTLLRGAFSPFGNIIDLSMDPPRNCAFVTYEKMESADQAVAELNGTQVESVQL 321

  Fly   230 QVQLARRQPQIEPINDASSSAVWSSIAASKSQKGSHKDHREMVQYDED 277
            :|.:||:||.::.   |:..:||.|:|...|.||.|:|.|..:.|.:|
Mouse   322 KVNIARKQPMLDA---ATGKSVWGSLAVQNSPKGCHRDKRTQIVYSDD 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nelf-E	NP_648241.1	RRM_NELFE	162..236	CDD:240751	29/73 (40%)
Nelfe	NP_001039328.1	RRM_NELFE	254..328	CDD:240751	29/73 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	79	1.000	Domainoid score	I8710
eggNOG	1	0.900	-	-		E1_28IDD
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47031
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008215
OrthoInspector	1	1.000	-	-		oto93201
orthoMCL	1	0.900	-	-		OOG6_108083
Panther	1	1.100	-	-	LDO	PTHR17250
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4686
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.810