Protein Alignment foi and Slc39a12

DIOPT Version :9

• Sequence 1: NP_001261584.1
• Gene: foi / 38976
• FlyBaseID: FBgn0024236
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: XP_038951487.1
• Gene: Slc39a12 / 291328
• RGDID: 1309305
• Length: 706
• Species: Rattus norvegicus
• Alignment Length: 684
• Identity: 154/684 - (22%)
• Similarity: 266/684 - (38%)
• Gaps: 209/684 - (30%)

  Fly    14 LCAHRLHCQD-----HIESLLGPAR------VTTHNSQDQL-NARVY--TNLSPSSETTDRRQQ- 63
            :|:.:|:..:     ::.|||...:      ::...:.|.| :.|.|  |:.||..||...:::
  Rat   127 ICSSKLNMSNREYEFYLHSLLSLRQDEDSYFLSEKETDDILASTRKYFGTSTSPCMETKILQRES 191

  Fly    64 --RSASGDDDTFNYSISPPSRREKRHA---GHEHGPTSESRVPQITQYYLEKLMAQDELMNSSGF 123
              :|::|.|:.....::..........   |.:..|:     |.....|:...:.:...::.|..
  Rat   192 GIQSSNGADEKMLPQLAATIIALSLQGVCLGRKDSPS-----PDDFTEYIFSFLNRTNALHLSEL 251

  Fly   124 DGLLQQLSLHSLASGASEGTCVPGSRL----------VHHVQPHDHHHAHHHEEEDHSLQLNNCT 178
            :.||..||        :...|...:.|          ||.::......|......|||:..:...
  Rat   252 EELLNMLS--------TRRACTKINTLHEHQRKQNTAVHGLRDPKSAAAMDKVSGDHSVSWDQAC 308

  Fly   179 LIQNGTTSNVICPSLPNNNTHPLGKEAKNFTLSDKDLLHLCPILLYELKAQSGGCIEPAILSDID 243
            .    :...::...|.|:::..:.||         |...|.|.::.:|.:.|  |..|   .|..
  Rat   309 F----SAQQLVEIFLQNHSSLSISKE---------DFKQLSPGIIQQLLSCS--CQVP---RDQK 355

  Fly   244 TTEELLEAEKDKDIFYVWIYAFISVFACGILGLVGVAIIPFMG-SRYYKYIIQYLVALAVGTMTG 307
            ........||       :.|:.::|....:..::|.|::.|.. ...|..|:|..|.|||||::|
  Rat   356 AKPPPTTLEK-------YGYSTVAVTLLTLGSMLGTALVLFHSCEENYSLILQLFVGLAVGTLSG 413

  Fly   308 DALLHLLPHSLA----------GQDERGMIMKGLGCLGGIIFFYVMEHALTMISEWRKSVEKKET 362
            ||||||:|..|.          ..:.:..|.|.||.||||..|:::|....::
  Rat   414 DALLHLIPQVLGLHKQEAELGHFHESQSPIWKLLGLLGGIHGFFLIEKCFILL------------ 466

  Fly   363 KKPSRAKVMRDPDSSVNNSVAGDKICKQKYSSYPYCYDEITMNNKQSEWMHLPFDVAAGAGGDAP 427
                                                   ::.|.|     .||
  Rat   467 ---------------------------------------VSPNTK-----GLP------------ 475

  Fly   428 SVAELRNGVGDHDGSNDMAAAAESLISPLHTNCV----EMNHHNHNHKHNSHQQNHEGQDSNTIV 488
                |.||   |.|               ||:.:    |:|..:...|..|..|....:||.|
  Rat   476 ----LVNG---HAG---------------HTHHLGLSPELNDQSGGGKSISTIQLKGPEDSQT-- 516

  Fly   489 TDLDGNAVYAVNKAKDKDSRNDHVTVILREHESSHHGHSHRHGHVHSPPETLSAVAWMIIMGDGL 553
            .:|....|.|.|:.:                                  :|:|.:|.|:::||||
  Rat   517 AELPKGNVPASNRNR----------------------------------KTISLLAVMVLVGDGL 547

  Fly   554 HNFTDGMAIGAAFAENIAGGFSTSLAVFCHELPHELGDFAILIKAGMSVKSAVYYNLLTGVLSFI 618
            |||.||:.||.||:.::..|.:|::|:.|||:|||:||||:|:.:|:|:::|:..|.|:.:.:||
  Rat   548 HNFADGLVIGTAFSSSLESGVTTTIAILCHEIPHEMGDFAVLLSSGLSIRTAILMNFLSALTAFI 612

  Fly   619 GMIFGIAFGQSQDVAQWMFAVAAGLFIYIALVDM 652
            |:..|::......|..|:..|.||:|:|::||.|
  Rat   613 GLYIGLSVSADPRVQDWILTVTAGMFLYLSLVGM 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foi	NP_001261584.1	Zip	258..684	CDD:280666	106/410 (26%)
Slc39a12	XP_038951487.1	ZIP4_domain	62..221	CDD:408101	17/93 (18%)
		Zip	368..646	CDD:396884	105/403 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0428
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D657777at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12191
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920