DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment foi and AgaP_AGAP011178

DIOPT Version :9

Sequence 1:	NP_001261584.1	Gene:	foi / 38976	FlyBaseID:	FBgn0024236	Length:	706	Species:	Drosophila melanogaster
Sequence 2:	XP_309469.4	Gene:	AgaP_AGAP011178 / 1270749	VectorBaseID:	AGAP011178	Length:	398	Species:	Anopheles gambiae

Alignment Length:	490	Identity:	83/490 - (16%)
Similarity:	143/490 - (29%)	Gaps:	198/490 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   262 IYAFISVFACGILGLVGVAIIPFMGSRYYK------------YIIQYLVALAVGTMTGDALLHLL 314
            :..|.....||        ::||...|::.            ::|:.|::...|.:.....||||
Mosquito    48 VVLFSVSMVCG--------LVPFKLVRWFNLNPATPSGGTHLFLIRLLLSFGGGALLSTTFLHLL 104

  Fly   315 P---HSLAGQDERGMIMK------GLG---CLGGIIFFYVMEHALTMISEW--RKSVEKKETKKP 365
            |   ||:....|.|.:..      .||   ...|....|:.|.   ::..|  |:|...:...:.
Mosquito   105 PEINHSIEALVETGALPAPDELPFPLGEFLLTSGFFMIYLTEE---LVHWWMHRRSANARRIARS 166

  Fly   366 SRAKVMRDPDSSVNNSVAGDKICKQKYSSYPYCYDEITMNNKQSEWMHLPFDVAAGAGGDAPSVA 430
            .:.                                                     |.|.:.::.
Mosquito   167 EKT-----------------------------------------------------APGGSSTMV 178

  Fly   431 ELRNGVGDHDGSNDMAAAAESLISPLHTNCVEMNHHNHNHKHNSHQQNHEGQDSNTI----VTDL 491
            .:..|...||                         |.|.|.|.        ...|..    |||:
Mosquito   179 PIDGGASKHD-------------------------HAHGHSHL--------PIGNVTAVYPVTDV 210

  Fly   492 DGNAVY-AVNKAKDKDSRNDHVTVILREHESSHHGHSHRHGHVHSPPETLSAVAWMIIMGDGLHN 555
            ||..|. :|.......|.|..:..:|                              |::...:|.
Mosquito   211 DGTQVVPSVVPVPPAPSANGPLRGLL------------------------------IVLALSIHE 245

  Fly   556 FTDGMAIGAAFAEN----IAGGFSTS--LAVFCHELPHELGDFAILIKAGMSVKSAVYYNLLTGV 614
            ..:|:|:|...:.:    :.|..::.  :..||..       |.:|: |.:..:.||.|..:..|
Mosquito   246 LFEGLAVGLERSPSAVWLLFGAVASHKFVIAFCVA-------FELLV-ASVRFRIAVLYIFVYSV 302

  Fly   615 LSFIGMIFGIAFGQ-SQDVAQWMFAV-------AAGLFIYIALVDMMPEISASHKSLGQFLLQIL 671
            :|.:|:..|||... |.|..|.:..|       |:|..||:...:::.:.:....:.|..:|.|.
Mosquito   303 VSPVGIGIGIALSSVSSDTNQTIEVVSVVLQGLASGTLIYVIFFEILAKDAGHSHANGTIILTIC 367

  Fly   672 GMLSGVGIMLLIALYEGDLMSAFGTAGAASHQHAH 706
                              |::....|...||.|.|
Mosquito   368 ------------------LLTFLCFAAGHSHDHGH 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
foi	NP_001261584.1	Zip	258..684	CDD:280666	77/466 (17%)
AgaP_AGAP011178	XP_309469.4	Zip	41..373	CDD:280666	78/477 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910