Protein Alignment foi and slc39a5

DIOPT Version :10

• Sequence 1: NP_523974.3
• Gene: foi / 38976
• FlyBaseID: FBgn0024236
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: XP_012811933.2
• Gene: slc39a5 / 100145325
• XenbaseID: XB-GENE-952069
• Length: 618
• Species: Xenopus tropicalis
• Alignment Length: 676
• Identity: 182/676 - (26%)
• Similarity: 282/676 - (41%)
• Gaps: 219/676 - (32%)

  Fly   106 YYLEKLM---AQDELMNSSGFDGLLQQLSLHSLASGASEGTCVPGSRLVH----HVQPHDHHHAH 163
            |||::|.   .:::.:...|...|||.|.|..:.....|.|.:....:.|    .||.:.|.|.|
 Frog    68 YYLQQLFHLYGENDTLTYEGLTLLLQNLGLGKVQVVEIEHTDLGHDHVSHLDILDVQGNKHSHMH 132

  Fly   164 HHEEEDHS--------LQLNNCTLIQ--NGTTSNVICPSL----------------PNNNTHPLG 202
            ...|...|        :|..|...::  :|.|..|...||                |..|..|..
 Frog   133 SSREHLQSSTTMPLPVIQTKNARSVEVNSGITRPVHAVSLKSTQMPPHNGKRGSTQPGQNQRPTE 197

  Fly   203 KEAK-------------------------NFTLS------DKDLLHLCPILLYELKAQSGGCIEP 236
            ...|                         ||.||      .:....|||.|||::  .|..||.
 Frog   198 DILKRVIQLHHSQFSHQHENCLNVTQLLMNFGLSWVSAITPQQFSLLCPALLYQI--DSRVCIH- 259

  Fly   237 AILSDIDTTEELLEAEKDKDIFYVWIYAFISVFACGIL--------GLVGVAIIPFMGSRYYKYI 293
                   .::||..::.|..      .|.:.|...|.|        .|:.||.:|.:....::|:
 Frog   260 -------HSDELTNSKPDSK------QALLQVLGWGALAVTVISAPSLLAVAFVPLLRRPLFRYL 311

  Fly   294 IQYLVALAVGTMTGDALLHLLPHSLAGQDERG-----------MIMKGLGCLGGIIFFYVMEHAL 347
            :::||||||||:.|||||||:||  |.:|..|           .::|||..|||:...:::|:.:
 Frog   312 LRFLVALAVGTLCGDALLHLMPH--AQEDHTGNQHGGKTHAIEPVLKGLSVLGGLYLLFLIENLM 374

  Fly   348 TMISEWRKSVEKKETKKPSRAKVMRDPDSSVNNSVAGDKICKQKYSSYPYCYDEITMNNKQSEWM 412
            .::.      ::::.|:.|:.:|           .|||:       ||
 Frog   375 GLLK------QRQQLKRLSKPEV-----------PAGDE-------SY----------------- 398

  Fly   413 HLPFDVAAGAGGDAPSVAELRNGVGDHDGSNDMAAAAESLISPLHTNCVEMNHHNHNHKHNSHQQ 477
                                             ..|...|.||:.:...|:
 Frog   399 ---------------------------------TTALWDLGSPVESEFCEV-------------- 416

  Fly   478 NHEGQDSNTIVTDLDGNAVYAVNKAKDKDSRNDHVTVILREHESSHHGHSHRHGHVHSPPETLSA 542
                  |........||...|:.:..:||:...|          ||.||||     :...:.::.
 Frog   417 ------SRAAEILQRGNEEVAIRRRDEKDAPAPH----------SHSGHSH-----NMASKGITE 460

  Fly   543 VAWMIIMGDGLHNFTDGMAIGAAFAENIAGGFSTSLAVFCHELPHELGDFAILIKAGMSVKSAVY 607
            :.||:::|||:||||||:||||||:...:||.||::|||||||||||||||:|:::|:.|:..::
 Frog   461 IVWMVLLGDGIHNFTDGLAIGAAFSSGFSGGLSTTVAVFCHELPHELGDFAVLLQSGVPVRKVLF 525

  Fly   608 YNLLTGVLSFIGMIFG-IAFGQSQDVAQWMFAVAAGLFIYIALVDMMPEISASHKSLG------Q 665
            ::|::..|||.|||.| :|...|..:..|:||..||:|:|:|||||:|::  .|:...      .
 Frog   526 FSLVSAFLSFFGMIIGAVASQNSAQITPWIFAATAGIFLYVALVDMLPQM--LHRETADPCQGKD 588

  Fly   666 FLLQILGMLSGVGIMLLIALYEGDLM 691
            .::..||.|.|..||..||||:..::
 Frog   589 CVIHSLGFLLGCAIMFCIALYQDQMV 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foi	NP_523974.3	Zip	258..684	CDD:396884	131/451 (29%)
slc39a5	XP_012811933.2	Zip	284..607	CDD:396884	128/435 (29%)