Protein Alignment foi and slc39a8

DIOPT Version :10

• Sequence 1: NP_523974.3
• Gene: foi / 38976
• FlyBaseID: FBgn0024236
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: XP_009305480.1
• Gene: slc39a8 / 100002893
• ZFINID: ZDB-GENE-050419-124
• Length: 443
• Species: Danio rerio
• Alignment Length: 613
• Identity: 158/613 - (25%)
• Similarity: 246/613 - (40%)
• Gaps: 207/613 - (33%)

  Fly   112 MAQDELMNSSGFDG------------LLQQLSLHSLASGASEGT------CVPGSRLVHHVQPHD 158
            |.:..|.|..||.|            .||.::....|:...||.      |:..|.|:
Zfish     1 MEESFLQNVLGFYGEESSLSVGNLELFLQLITSRRAAAVEDEGNPLKSAECLSLSELL------- 58

  Fly   159 HHHAHHHEEEDHSLQLNNCTLIQNGTTSN--VICPSLPNNNTHPLGKEAKNFTLSDKDLLHLCPI 221
                       .:..|:|.:::   :.||  ::||::.|                 :.|:..||.
Zfish    59 -----------SAFGLSNASVV---SVSNLEMMCPAILN-----------------QVLIPACPY 92

  Fly   222 LLYELKAQSGGCIEPAILSDIDTTEELLEAEKDKDIFYVWIYAFISVFACGILGLVGVAIIPFMG 286
            ....|.|.       |.:||                ..||.|.|::|....:..|:|:.::||..
Zfish    93 TSSNLNAS-------ASISD----------------HKVWGYGFLAVTVINLAALLGLFLVPFTK 134

  Fly   287 SRYYKYIIQYLVALAVGTMTGDALLHLLPHSLAGQDER--GMIMKGLGCLGGIIFFYVMEHALTM 349
            .:|:..::.|.:.||:||:..:|:|.|:|.:| |.|.:  ..::..:|..||....:|.|..|.|
Zfish   135 KKYFPKVLMYFIGLAIGTLFSNAVLQLIPEAL-GLDPKDDNYVLNVVGIFGGFYILFVTERILKM 198

  Fly   350 ISEWRKSVEKKETKKPSRAKVMRDPDSSVNNSVAGDKICKQKYSSYPYCYDEITMNNKQSEWMHL 414
            :.:                     .|:.:.:|                               |.
Zfish   199 VLK---------------------TDTELGHS-------------------------------HF 211

  Fly   415 P----FDVAAGAGGDAPSVAELRNGVGDHDGSNDMAAAAESLISPLHTNCVEMNHHNHNHKHNSH 475
            |    .||         :::.:.|.|...:.|.|:.           ||       |.||:.||.
Zfish   212 PPLQSSDV---------TISTISNDVVISNISGDII-----------TN-------NTNHEQNSI 249

  Fly   476 QQNHEGQDSNTIVTDLDGNAVYAVNKAKDKDSRNDHVTVILREHESSHHGHSHRHGHVHSPPETL 540
            .:. ....|.:...:.:..|::|....|.....|                              :
Zfish   250 SEK-SNNPSESPAVEQNACALFACRWLKGSAMSN------------------------------I 283

  Fly   541 SAVAWMIIMGDGLHNFTDGMAIGAAFAENIAGGFSTSLAVFCHELPHELGDFAILIKAGMSVKSA 605
            ..|||||.:.|.||||.||:||||:|..::..|||||:|:||.|.|||||||.||:.:||||..|
Zfish   284 KTVAWMITVSDALHNFIDGLAIGASFTLSLLSGFSTSIAIFCEEFPHELGDFVILLNSGMSVGQA 348

  Fly   606 VYYNLLTGVLSFIGMIFGIAFGQSQDVAQWMFAVAAGLFIYIALVDMMPE---ISASHKSLGQ-- 665
            .::|||:.:..::|:..||..| |......:||:|.|:|:||:|.||.||   |.|||....|
Zfish   349 AFFNLLSAMCCYLGLALGILLG-SNFAPNAIFAIAGGMFLYISLADMFPEMNSIMASHTKDYQER 412

  Fly   666 ---FLLQILGMLSGVGIMLLIALYEGDL 690
               ||:|..|:|:|..|:|||.|:.||:
Zfish   413 VVFFLIQNAGLLTGFTIILLITLFAGDI 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
foi	NP_523974.3	Zip	258..684	CDD:396884	125/439 (28%)
slc39a8	XP_009305480.1	Zip	108..434	CDD:396884	125/437 (29%)