Protein Alignment GstO1 and CLIC3

DIOPT Version :10

• Sequence 1: NP_648237.1
• Gene: GstO1 / 38975
• FlyBaseID: FBgn0035907
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_004660.2
• Gene: CLIC3 / 9022
• HGNCID: 2064
• Length: 236
• Species: Homo sapiens
• Alignment Length: 221
• Identity: 49/221 - (22%)
• Similarity: 84/221 - (38%)
• Gaps: 38/221 - (17%)

  Fly    18 DDGILKLYSMRFCPYAHRVHLVLDAKKIPYHAIYINLRDKPEWFSLVSSSTKVPALELVKEQGNP 82
            :||    .|:..||...|:.:||..|.:|:....::.|..|:.....:..:::|.|    ...:.
Human    14 EDG----ESVGHCPSCQRLFMVLLLKGVPFTLTTVDTRRSPDVLKDFAPGSQLPIL----LYDSD 70

  Fly    83 VLIESLIICDYLDEKY--PEVP-LYPKDLLKKAQEKILIERFGQFI--------NAFYYLLLHDN 136
            ...::|.|.|:|:|..  |:.| |.|:..........:..:|..||        .|.|..||
Human    71 AKTDTLQIEDFLEETLGPPDFPSLAPRYRESNTAGNDVFHKFSAFIKNPVPAQDEALYQQLL--- 132

  Fly   137 PEQLVDTDHY---------AGLVVYEEELKRRCTKFFGGDSPGMLDYMMWPWCERFDSLKYTFEQ 192
             ..|...|.|         ||    |.:|:....:|..||...:.|..:.|.....|::...|.|
Human   133 -RALARLDSYLRAPLEHELAG----EPQLRESRRRFLDGDRLTLADCSLLPKLHIVDTVCAHFRQ 192

  Fly   193 KFELSPERFPTLIKWRDLMIQDRAVK 218
              ...|.....:.::.|..:|::..|
Human   193 --APIPAELRGVRRYLDSAMQEKEFK 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstO1	NP_648237.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	3..95	CDD:469754	17/76 (22%)
		GST_C_Omega	109..234	CDD:198293	26/127 (20%)
CLIC3	NP_004660.2	Required for insertion into the membrane. /evidence=ECO:0000250	1..88		19/81 (23%)
		O-ClC	5..229	CDD:129941	49/221 (22%)
		G-site. /evidence=ECO:0000305|PubMed:28198360, ECO:0000305|PubMed:37759794	22..25		2/2 (100%)