DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstO1 and eEF1gamma

DIOPT Version :9

Sequence 1:	NP_648237.1	Gene:	GstO1 / 38975	FlyBaseID:	FBgn0035907	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001189308.1	Gene:	eEF1gamma / 44791	FlyBaseID:	FBgn0029176	Length:	431	Species:	Drosophila melanogaster

Alignment Length:	208	Identity:	41/208 - (19%)
Similarity:	74/208 - (35%)	Gaps:	45/208 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 KVPALELVKEQGNPVLIESLIICDYLDEKYPEVPLYPKDLLKKAQEKILIERFGQFIN------- 126
            ||||.|..:.|             ||.|......|...:.|:..:...:..:..|:|:
  Fly    54 KVPAFETAEGQ-------------YLSESNAIAYLLANEQLRGGKCPFVQAQVQQWISFADNEIV 105

  Fly   127 ----AFYYLLLHDNPEQLVDT-DHYAGLVVYEEELKRRCTKFFGGDSPGMLDYMMWPWCERFDSL 186
                |:.:.||...|:|...| ...|..|:.:...|.:...|..|:...:.|.::      |.||
  Fly   106 PASCAWVFPLLGILPQQKNSTAKQEAEAVLQQLNQKLQDATFLAGERITLADIVV------FSSL 164

  Fly   187 KYTFEQKFELS-PERFPTLIKWRDLMIQDRAV-----------KCFYLDGQTHAKYMNSRRSGQA 239
            .:.:|...|.| ...|..:.:|...::..:.|           |....|.:.:|::  ..::|.|
  Fly   165 LHLYEYVLEPSVRSAFGNVNRWFVTILNQKQVQAVVKDYKLCEKALVFDPKKYAEF--QAKTGAA 227

  Fly   240 DYNMLYNEAKRVK 252
            .......:.|:.|
  Fly   228 KPQQQAQQQKQEK 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstO1	NP_648237.1	Thioredoxin_like	3..95	CDD:294274	7/25 (28%)
		GstA	22..216	CDD:223698	33/159 (21%)
		GST_C_Omega	109..234	CDD:198293	27/148 (18%)
eEF1gamma	NP_001189308.1	GST_N_EF1Bgamma	4..79	CDD:239342	10/37 (27%)
		GstA	5..187	CDD:223698	32/151 (21%)
		GST_C_EF1Bgamma_like	90..209	CDD:198290	23/124 (19%)
		EF1G	271..376	CDD:279041
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459934
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930