DRSC/TRiP Functional Genomics Resources

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Protein Alignment GstO1 and GSTO2

DIOPT Version :10

Sequence 1:NP_648237.1 Gene:GstO1 / 38975 FlyBaseID:FBgn0035907 Length:254 Species:Drosophila melanogaster
Sequence 2:NP_899062.1 Gene:GSTO2 / 119391 HGNCID:23064 Length:243 Species:Homo sapiens


Alignment Length:256 Identity:84/256 - (32%)
Similarity:123/256 - (48%) Gaps:52/256 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MSNTQHLTIGS----PKPVFPDDGILKLYSMRFCPYAHRVHLVLDAKKIPYHAIYINLRDKPEWF 61
            ||.....|:|.    |.||  .:|::::||||||||:||..|||.||.|.:..:.||||:||||:
Human     1 MSGDATRTLGKGSQPPGPV--PEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWY 63

  Fly    62 SLVSSSTKVPALELVKEQGNPVLIESLIICDYLDEKYPEVPLYPKDLLKKAQEKILIERFGQFIN 126
            ........:|.||..:.|   ::.||:|.|:|||:.||...|:|.|..::|::|:|:|.|.:   
Human    64 YTKHPFGHIPVLETSQCQ---LIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCK--- 122

  Fly   127 AFYYLLLHDNPEQLVD--------------TDHYAGLVVYEEELKRRCTKFFGGDSPGMLDYMMW 177
                 :.|...|.||.              ...::.|   ||.|:.:.|.||||....|:||::|
Human   123 -----VPHLTKECLVALRCGRECTNLKAALRQEFSNL---EEILEYQNTTFFGGTCISMIDYLLW 179

  Fly   178 PWCER------FDSLKYTFEQKFELSPERFPTLIKWRDLMIQDRAVKCFYLDGQTHAKYMN 232
            ||.||      .|.:.:|            |.|..|...|..|..|....:|......::|
Human   180 PWFERLDVYGILDCVSHT------------PALRLWISAMKWDPTVCALLMDKSIFQGFLN 228

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GstO1NP_648237.1 Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold 3..95 CDD:469754 39/95 (41%)
GST_C_Omega 109..234 CDD:198293 36/144 (25%)
GSTO2NP_899062.1 Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold 7..94 CDD:469754 39/91 (43%)
GST_C_Omega 108..230 CDD:198293 36/144 (25%)

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