Protein Alignment GstO1 and Clic1

DIOPT Version :10

• Sequence 1: NP_648237.1
• Gene: GstO1 / 38975
• FlyBaseID: FBgn0035907
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_254279.1
• Gene: Clic1 / 114584
• MGIID: 2148924
• Length: 241
• Species: Mus musculus
• Alignment Length: 204
• Identity: 38/204 - (18%)
• Similarity: 79/204 - (38%)
• Gaps: 63/204 - (30%)

  Fly    30 CPYAHRVHLVLDAKKIPYHAIYINLRDKPEWFSLVSSSTKVPALELVKEQGNPVLIESLIICDYL 94
            ||::.|:.:||..|.:.::...::.:.:.|....:....::|.|    ..|..|..::..|.::|
Mouse    24 CPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFL----LYGTEVHTDTNKIEEFL 84

  Fly    95 D-----EKYPEV-PLYPK------DLLKKAQ--------------EKILIERFGQFINAFYYLLL 133
            :     .:||:: .|.|:      |:..|..              ||.|::.          |.:
Mouse    85 EAMLCPPRYPKLAALNPESNTSGLDIFAKFSAYIKNSNPALNDNLEKGLLKA----------LKV 139

  Fly   134 HDN------PEQLVDTDHYAGLVVYEEELKRRCTKFFGGDSPGMLDYMMWP-------WCERFDS 185
            .||      ||::.:|.      ..:|.:.:|  ||..|:...:.|..:.|       .|:::..
Mouse   140 LDNYLTSPLPEEVDETS------AEDEGISQR--KFLDGNELTLADCNLLPKLHIVQVVCKKYRG 196

  Fly   186 LKYTFEQKF 194
              :|..:.|
Mouse   197 --FTIPEAF 203

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstO1	NP_648237.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	3..95	CDD:469754	12/64 (19%)
		GST_C_Omega	109..234	CDD:198293	20/113 (18%)
Clic1	NP_254279.1	Required for insertion into the membrane. /evidence=ECO:0000250	2..90		13/69 (19%)
		O-ClC	6..241	CDD:129941	38/204 (19%)
		G-site. /evidence=ECO:0000250|UniProtKB:O00299	24..27		2/2 (100%)