DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstO2 and CAM1

DIOPT Version :9

Sequence 1:	NP_729388.1	Gene:	GstO2 / 38974	FlyBaseID:	FBgn0035906	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_015277.1	Gene:	CAM1 / 856059	SGDID:	S000005969	Length:	415	Species:	Saccharomyces cerevisiae

Alignment Length:	209	Identity:	47/209 - (22%)
Similarity:	81/209 - (38%)	Gaps:	33/209 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 RVRLMLAAKHIEHHKIYVDLI----EKPEWYKDFSPLGKVPALQLTGVKDQPTLVESLIIAEYL- 95
            |:|..:....::..|:.|.::    ...::.:|| ||.||||  ..|.|.. .|.|::.|..||
Yeast    11 RIRTWVPRGLVKALKLDVKVVTPDAAAEQFARDF-PLKKVPA--FVGPKGY-KLTEAMAINYYLV 71

  Fly    96 ----DQQYPQTRLFPTDPLQKALDKILIERFA------PVVSAIYPV---LTCNPNAPKDAIPNF 147
                |.:.....|...|.|......|..:..|      .:.:.|.|:   ...|..:...|:...
Yeast    72 KLSQDDKMKTQLLGADDDLNAQAQIIRWQSLANSDLCIQIANTIVPLKGGAPYNKKSVDSAMDAV 136

  Fly   148 ENALDVFEVELGKRGTPYFAGQHIGIVDYMIWPWFERFPSMKINTEQKYE-------LDTKRFEK 205
            :..:|:||..|  :...|.|.::|.:.|.:....|.|:......||.:.:       .:|.|...
Yeast   137 DKIVDIFENRL--KNYTYLATENISLADLVAASIFTRYFESLFGTEWRAQHPAIVRWFNTVRASP 199

  Fly   206 LLK--WRDLMTQDE 217
            .||  ::|....|:
Yeast   200 FLKDEYKDFKFADK 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstO2	NP_729388.1	Thioredoxin_like	5..96	CDD:294274	19/68 (28%)
		GstA	25..215	CDD:223698	46/205 (22%)
		GST_C_Omega	110..235	CDD:198293	25/126 (20%)
CAM1	NP_015277.1	GST_N_EF1Bgamma	4..73	CDD:239342	19/65 (29%)
		GST_C_EF1Bgamma_like	92..214	CDD:198290	24/124 (19%)
		EF1G	255..359	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345041
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930