DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstO2 and TEF4

DIOPT Version :9

Sequence 1:	NP_729388.1	Gene:	GstO2 / 38974	FlyBaseID:	FBgn0035906	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_012842.1	Gene:	TEF4 / 853781	SGDID:	S000001564	Length:	412	Species:	Saccharomyces cerevisiae

Alignment Length:	235	Identity:	53/235 - (22%)
Similarity:	93/235 - (39%)	Gaps:	63/235 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 IEHHKIYVDLI--EKPEWYKDFSPLGKVPA-LQLTGVKDQPTLVESLIIAEYLDQQY----PQTR 103
            |.:.|:.|.::  |:...:....||.:.|| |...|:|    |.|:|.|..||..|.    .:.|
Yeast    21 ISYFKLDVKIVDLEQSSEFASLFPLKQAPAFLGPKGLK----LTEALAIQFYLANQVADEKERAR 81

  Fly   104 LFPTDPLQKALDKILIERFAPVVSA------IYPVLTCN---PNAPKDAIPNF---ENALDVFEV 156
            |..:|.::|:  :||  |:|.:.::      ..|.|:..   |...||....|   :|...||:.
Yeast    82 LLGSDVIEKS--QIL--RWASLANSDVMSNIARPFLSFKGLIPYNKKDVDACFVKIDNLAAVFDA 142

  Fly   157 ELGKRGTPYFAGQHIGIVDY------------MIWP-WFERFPSMKINTEQKYELDTKRFEKLLK 208
            .|  |...:.|.::|.:.|.            ::.| |..:.|                  .|::
Yeast   143 RL--RDYTFVATENISLGDLHAAGSWAFGLATILGPEWRAKHP------------------HLMR 187

  Fly   209 WRDLMTQDEVVQKTALDVQLHAEFQKSKTLGNPQYDIAFK 248
            |.:.:....:|:....:|:|   .:|:.|...|:...|.|
Yeast   188 WFNTVAASPIVKTPFAEVKL---AEKALTYTPPKKQKAEK 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstO2	NP_729388.1	Thioredoxin_like	5..96	CDD:294274	16/52 (31%)
		GstA	25..215	CDD:223698	45/200 (23%)
		GST_C_Omega	110..235	CDD:198293	27/149 (18%)
TEF4	NP_012842.1	GST_N_EF1Bgamma	4..72	CDD:239342	17/54 (31%)
		GST_C_EF1Bgamma_like	89..211	CDD:198290	27/148 (18%)
		EF1G	253..356	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345045
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930