DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstO2 and gsto2

DIOPT Version :9

Sequence 1:	NP_729388.1	Gene:	GstO2 / 38974	FlyBaseID:	FBgn0035906	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_001007373.1	Gene:	gsto2 / 492500	ZFINID:	ZDB-GENE-041114-67	Length:	240	Species:	Danio rerio

Alignment Length:	247	Identity:	86/247 - (34%)
Similarity:	131/247 - (53%)	Gaps:	13/247 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MALPQKHFKRGSTKPELPEDGVPRFFSMAFCPFSHRVRLMLAAKHIEHHKIYVDLIEKPEWYKDF 65
            ||...|...:..:.|....:|..|.:||.||||:.|.||:|.||.::|..|.::|:.||:|:...
Zfish     1 MASSPKCLGKECSAPGPVPNGQIRLYSMRFCPFAQRTRLVLTAKGVKHDIININLVSKPDWFLKK 65

  Fly    66 SPLGKVPALQLTGVKDQPTLVESLIIAEYLDQQYPQTRLFPTDPLQKALDKILIERFAPVVSAIY 130
            :|.|.||.|:.:..:   .:.||.|..||||:.||:.:|.|:||.::|..|:|:|.::.|:...|
Zfish    66 NPFGTVPVLETSSGQ---VIYESPITCEYLDEVYPEKKLLPSDPFERAQQKMLLELYSKVIPYFY 127

  Fly   131 PVLTCNPNAPKD---AIPNFENALDVFEVELGKRGTPYFAGQHIGIVDYMIWPWFERFPSMKINT 192
            .: :......:|   |...|...|......|..:.|.||.|..|.::||:|||||||...|.:
Zfish   128 KI-SMGKKRGEDVSTAEAEFTEKLLQLNEALANKKTKYFGGDSITMIDYLIWPWFERAEMMGV-- 189

  Fly   193 EQKYELDTKRFEKLLKWRDLMTQDEVVQKTALDVQLHAEFQKSKTLGNPQYD 244
              |:.|  .:..:|.||.:||.:|.||:.|..:..:|..|..|...|.|.||
Zfish   190 --KHCL--AKTPELRKWIELMFEDPVVKATMFNTDVHKVFFDSYMDGKPNYD 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstO2	NP_729388.1	Thioredoxin_like	5..96	CDD:294274	32/90 (36%)
		GstA	25..215	CDD:223698	69/192 (36%)
		GST_C_Omega	110..235	CDD:198293	39/127 (31%)
gsto2	NP_001007373.1	GST_N_Omega	4..93	CDD:239353	32/91 (35%)
		GstA	25..210	CDD:223698	69/194 (36%)
		GST_C_Omega	107..229	CDD:198293	39/128 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11791
eggNOG	1	0.900	-	-		E1_KOG0406
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	180	1.000	Inparanoid score	I3986
OMA	1	1.010	-	-		QHG48297
OrthoDB	1	1.010	-	-		D1225872at2759
OrthoFinder	1	1.000	-	-		FOG0001358
OrthoInspector	1	1.000	-	-		mtm6382
orthoMCL	1	0.900	-	-		OOG6_100366
Panther	1	1.100	-	-	O	PTHR43968
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16830
SonicParanoid	1	1.000	-	-		X130
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.870