DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstO2 and gsto1

DIOPT Version :9

Sequence 1:	NP_729388.1	Gene:	GstO2 / 38974	FlyBaseID:	FBgn0035906	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_001002621.1	Gene:	gsto1 / 436894	ZFINID:	ZDB-GENE-040718-365	Length:	240	Species:	Danio rerio

Alignment Length:	248	Identity:	90/248 - (36%)
Similarity:	136/248 - (54%)	Gaps:	15/248 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MALPQKHFKRGSTKP-ELPEDGVPRFFSMAFCPFSHRVRLMLAAKHIEHHKIYVDLIEKPEWYKD 64
            ||..||...:||..| .:|:|.: |.:||.||||:.|.||:|.||.|::..|.::|..||:|:.:
Zfish     1 MAASQKCLGKGSPAPGPVPKDHI-RLYSMRFCPFAQRTRLVLNAKGIKYDTININLKNKPDWFLE 64

  Fly    65 FSPLGKVPALQLTGVKDQPTLVESLIIAEYLDQQYPQTRLFPTDPLQKALDKILIERFAPVVSAI 129
            .:|||.||.|:   .:....:.||.|..||||:.||:.:|.|.||.::|..::|:|.|:.|....
Zfish    65 KNPLGLVPVLE---TQSGQVIYESPITCEYLDEVYPEKKLLPFDPFERAQQRMLLELFSKVTPYF 126

  Fly   130 YPVLTCNPNAPKDAI---PNFENALDVFEVELGKRGTPYFAGQHIGIVDYMIWPWFERFPSMKIN 191
            |.: ..|....:|..   ...::.|..|...|.|:.:.:|.|..|.::|||:||||||..:|.:
Zfish   127 YKI-PVNRTKGEDVSALETELKDKLSQFNEILLKKKSKFFGGDSITMIDYMMWPWFERLETMNL- 189

  Fly   192 TEQKYELDTKRFEKLLKWRDLMTQDEVVQKTALDVQLHAEFQKSKTLGNPQYD 244
               |:.||..  .:|.||.:.|.:|..|:.|....:.:..|.||...|||.||
Zfish   190 ---KHCLDGT--PELKKWTERMMEDPTVKATMFSTETYMVFYKSYMEGNPNYD 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstO2	NP_729388.1	Thioredoxin_like	5..96	CDD:294274	37/91 (41%)
		GstA	25..215	CDD:223698	69/192 (36%)
		GST_C_Omega	110..235	CDD:198293	36/127 (28%)
gsto1	NP_001002621.1	GST_N_Omega	4..93	CDD:239353	37/92 (40%)
		GstA	25..210	CDD:223698	69/194 (36%)
		GST_C_Omega	107..229	CDD:198293	37/128 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	49	1.000	Domainoid score	I11791
eggNOG	1	0.900	-	-		E1_KOG0406
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	180	1.000	Inparanoid score	I3986
OMA	1	1.010	-	-		QHG48297
OrthoDB	1	1.010	-	-		D1225872at2759
OrthoFinder	1	1.000	-	-		FOG0001358
OrthoInspector	1	1.000	-	-		mtm6382
orthoMCL	1	0.900	-	-		OOG6_100366
Panther	1	1.100	-	-	O	PTHR43968
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16830
SonicParanoid	1	1.000	-	-		X130
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.870