Protein Alignment GstO2 and GSTZ1

DIOPT Version :10

• Sequence 1: NP_729388.1
• Gene: GstO2 / 38974
• FlyBaseID: FBgn0035906
• Length: 251
• Species: Drosophila melanogaster
• Sequence 2: NP_001350632.1
• Gene: GSTZ1 / 2954
• HGNCID: 4643
• Length: 217
• Species: Homo sapiens
• Alignment Length: 196
• Identity: 52/196 - (26%)
• Similarity: 86/196 - (43%)
• Gaps: 59/196 - (30%)

  Fly    17 LPEDGVPRFFSMAFCPFSHRVRLMLAAKHIEHHKIYVDLIEK--PEWYKDF---SPLGKVPALQL 76
            :.|.|.|..:|......|.|||:.||.|.|::..:.::||:.  .::.|||   :|:.:||.|::
Human     1 MTESGKPILYSYFRSSCSWRVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVPTLKI 65

  Fly    77 TGVKDQPTLVESLIIAEYLDQQYPQTRLFPTDPLQKALDKILIERFAPVVSAIYPV--------- 132
            .|:    |:.:||.|.|||::..|..||.|.||.::|..:::.:..|   ..|.|:
Human    66 DGI----TIHQSLAIIEYLEEMRPTPRLLPQDPKKRASVRMISDLIA---GGIQPLQNLSVLKQV 123

  Fly   133 ------------LTCNPNAPKD---------------------AIPNFENALDVFEVELGKRGTP 164
                        :||..||.:.                     .:|...|| :.|:|:|    ||
Human   124 GEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANA-ERFKVDL----TP 183

  Fly   165 Y 165
            |
Human   184 Y 184

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstO2	NP_729388.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	5..96	CDD:469754	28/83 (34%)
		GST_C_Omega	110..235	CDD:198293	17/98 (17%)
GSTZ1	NP_001350632.1	maiA	8..212	CDD:273527	49/189 (26%)