Protein Alignment GstO2 and GSTT1

DIOPT Version :10

• Sequence 1: NP_729388.1
• Gene: GstO2 / 38974
• FlyBaseID: FBgn0035906
• Length: 251
• Species: Drosophila melanogaster
• Sequence 2: XP_054181554.1
• Gene: GSTT1 / 2952
• HGNCID: 4641
• Length: 289
• Species: Homo sapiens
• Alignment Length: 191
• Identity: 42/191 - (21%)
• Similarity: 76/191 - (39%)
• Gaps: 37/191 - (19%)

  Fly    62 YKDFSPLGKVPALQLTGVKDQP-TLVESLIIAEYLDQQYP-QTRLFPTDPLQKA-LDKILIERFA 123
            :...:||.|||||     ||.. ||.||:.|..||.::|. ....:|.|...:| :|:.|..:..
Human    94 FAQVNPLKKVPAL-----KDGDFTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHT 153

  Fly   124 PV---------VSAIYPVLTCNPNAPKD---AIPNFENALDVFEVELGKRGTPYFAGQHIGIVDY 176
            .:         ...::||....|.:|:.   .:...:..|.:.|.:. .:...:..|.||.:.|.
Human   154 TLRRSCLRALWHKVMFPVFLGEPVSPQTLAATLAELDVTLQLLEDKF-LQNKAFLTGPHISLADL 217

  Fly   177 -----MIWP------WFERFPSM-----KINTEQKYELDTKRFEKLLKWRDLMTQDEVVQK 221
                 ::.|      .||..|.:     ::......:|..:..|.:||.:|....|..:::
Human   218 VAITELMHPVGAGCQVFEGRPKLATWRQRVEAAVGEDLFQEAHEVILKAKDFPPADPTIKQ 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstO2	NP_729388.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	5..96	CDD:469754	15/34 (44%)
		GST_C_Omega	110..235	CDD:198293	23/141 (16%)
GSTT1	XP_054181554.1	GST_N_Theta	3..127	CDD:239348	16/37 (43%)
		GST_C_Theta	140..265	CDD:198292	19/125 (15%)