Protein Alignment GstO2 and CLIC4

DIOPT Version :10

• Sequence 1: NP_729388.1
• Gene: GstO2 / 38974
• FlyBaseID: FBgn0035906
• Length: 251
• Species: Drosophila melanogaster
• Sequence 2: NP_039234.1
• Gene: CLIC4 / 25932
• HGNCID: 13518
• Length: 253
• Species: Homo sapiens
• Alignment Length: 159
• Identity: 32/159 - (20%)
• Similarity: 57/159 - (35%)
• Gaps: 27/159 - (16%)

  Fly     1 MALPQKHFKRGSTKP------ELPEDGVPRFFSMAFCPFSHRVRLMLAAKHIEHHKIYVDLIEKP 59
            :::|....|....:|      :...||.    |:..||||.|:.::|..|.:......|||..||
Human     3 LSMPLNGLKEEDKEPLIELFVKAGSDGE----SIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKP 63

  Fly    60 EWYKDFSPLGKVPALQLTG-VKDQPTLVESLIIAEYLDQQYPQTRLFPTDPLQKALDKILIERFA 123
            ...::.:|....|.:.... ||.....:|..:.......:|  .:|.|..|........:..:|:
Human    64 ADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKY--LKLSPKHPESNTAGMDIFAKFS 126

  Fly   124 PVVSAIYPVLTCNPNAPKDAIPNFENALD 152
            ..:              |::.|....||:
Human   127 AYI--------------KNSRPEANEALE 141

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstO2	NP_729388.1	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold	5..96	CDD:469754	22/97 (23%)
		GST_C_Omega	110..235	CDD:198293	5/43 (12%)
CLIC4	NP_039234.1	Required for insertion into the membrane. /evidence=ECO:0000305	2..101		23/101 (23%)
		O-ClC	17..252	CDD:129941	30/145 (21%)
		G-site. /evidence=ECO:0000250|UniProtKB:Q9Z0W7	35..38		2/2 (100%)