DRSC/TRiP Functional Genomics Resources

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Protein Alignment GstO2 and GSTO2

DIOPT Version :10

Sequence 1:NP_729388.1 Gene:GstO2 / 38974 FlyBaseID:FBgn0035906 Length:251 Species:Drosophila melanogaster
Sequence 2:NP_899062.1 Gene:GSTO2 / 119391 HGNCID:23064 Length:243 Species:Homo sapiens


Alignment Length:244 Identity:83/244 - (34%)
Similarity:115/244 - (47%) Gaps:31/244 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 RGSTKPELPEDGVPRFFSMAFCPFSHRVRLMLAAKHIEHHKIYVDLIEKPEWYKDFSPLGKVPAL 74
            :||..|....:|:.|.:||.|||:|||.||:|.||.|.|..:.::|..|||||....|.|.:|.|
Human    11 KGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLRNKPEWYYTKHPFGHIPVL 75

  Fly    75 QLTGVKDQPTLVESLIIAEYLDQQYPQTRLFPTDPLQKALDKILIERFAPVVSAIYPVLT----- 134
            :.:..:   .:.||:|..||||..||..:|||.||.::|..|:|:|.|..|     |.||     
Human    76 ETSQCQ---LIYESVIACEYLDDAYPGRKLFPYDPYERARQKMLLELFCKV-----PHLTKECLV 132

  Fly   135 ---CNPNAP--KDAI-PNFENALDVFEVELGKRGTPYFAGQHIGIVDYMIWPWFERFPSMKINTE 193
               |.....  |.|: ..|.|..::.|.:    .|.:|.|..|.::||::||||||.....|   
Human   133 ALRCGRECTNLKAALRQEFSNLEEILEYQ----NTTFFGGTCISMIDYLLWPWFERLDVYGI--- 190

  Fly   194 QKYELDTKRFEKLLK-WRDLMTQDEVVQKTALDVQLHAEFQKSKTLGNP 241
                ||.......|: |...|..|..|....:|..:...|.......||
Human   191 ----LDCVSHTPALRLWISAMKWDPTVCALLMDKSIFQGFLNLYFQNNP 235

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GstO2NP_729388.1 Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold 5..96 CDD:469754 35/85 (41%)
GST_C_Omega 110..235 CDD:198293 37/136 (27%)
GSTO2NP_899062.1 Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold 7..94 CDD:469754 35/85 (41%)
GST_C_Omega 108..230 CDD:198293 37/137 (27%)

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