DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment se and gsto2

DIOPT Version :9

Sequence 1:	NP_648235.1	Gene:	se / 38973	FlyBaseID:	FBgn0086348	Length:	243	Species:	Drosophila melanogaster
Sequence 2:	NP_001007373.1	Gene:	gsto2 / 492500	ZFINID:	ZDB-GENE-041114-67	Length:	240	Species:	Danio rerio

Alignment Length:	247	Identity:	95/247 - (38%)
Similarity:	135/247 - (54%)	Gaps:	31/247 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 GRHLAKGSPMPDVPEDGILRLYSMRFCPFAQRVHLVLDAKQIPYHSIYINLTDKPEWLLEKNPQG 68
            |:..:...|:|    :|.:|||||||||||||..|||.||.:.:..|.|||..||:|.|:|||.|
Zfish     9 GKECSAPGPVP----NGQIRLYSMRFCPFAQRTRLVLTAKGVKHDIININLVSKPDWFLKKNPFG 69

  Fly    69 KVPALEIVREPGPPVLTESLLICEYLDEQYPLRPLYPRDPLKKVQDKLLIERFRAVLGAFFKASD 133
            .||.||   .....|:.||.:.||||||.||.:.|.|.||.::.|.|:|:|.:..|:..|:|.|.
Zfish    70 TVPVLE---TSSGQVIYESPITCEYLDEVYPEKKLLPSDPFERAQQKMLLELYSKVIPYFYKISM 131

  Fly   134 GGDLEPFWSGLDIYERE-------------LARRGTEFFGGEQTGILDYMIWPWCERLELLKLQR 185
            |..     .|.|:...|             ||.:.|::|||:...::||:||||.||.|::.::
Zfish   132 GKK-----RGEDVSTAEAEFTEKLLQLNEALANKKTKYFGGDSITMIDYLIWPWFERAEMMGVK- 190

  Fly   186 GEDYNYDQSRFPQLTLWLERMKRDPAVMAFYMEAEVQAEFLRTRSLGRPNYN 237
                 :..::.|:|..|:|.|..||.|.|.....:|...|..:...|:|||:
Zfish   191 -----HCLAKTPELRKWIELMFEDPVVKATMFNTDVHKVFFDSYMDGKPNYD 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
se	NP_648235.1	GST_N_Omega	3..95	CDD:239353	44/90 (49%)
		GstA	22..215	CDD:223698	84/205 (41%)
		GST_C_Omega	109..229	CDD:198293	38/132 (29%)
gsto2	NP_001007373.1	GST_N_Omega	4..93	CDD:239353	44/90 (49%)
		GstA	25..210	CDD:223698	80/198 (40%)
		GST_C_Omega	107..229	CDD:198293	38/132 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	92	1.000	Domainoid score	I7573
eggNOG	1	0.900	-	-		E1_KOG0406
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37971
Inparanoid	1	1.050	180	1.000	Inparanoid score	I3986
OMA	1	1.010	-	-		QHG48297
OrthoDB	1	1.010	-	-		D1225872at2759
OrthoFinder	1	1.000	-	-		FOG0001358
OrthoInspector	1	1.000	-	-		mtm6382
orthoMCL	1	0.900	-	-		OOG6_100366
Panther	1	1.100	-	-	O	PTHR43968
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16830
SonicParanoid	1	1.000	-	-		X130
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.870