Protein Alignment se and Clic4

DIOPT Version :10

• Sequence 1: NP_648235.1
• Gene: se / 38973
• FlyBaseID: FBgn0086348
• Length: 243
• Species: Drosophila melanogaster
• Sequence 2: NP_038913.1
• Gene: Clic4 / 29876
• MGIID: 1352754
• Length: 253
• Species: Mus musculus
• Alignment Length: 225
• Identity: 49/225 - (21%)
• Similarity: 85/225 - (37%)
• Gaps: 55/225 - (24%)

  Fly     7 LAKGSPMPDVPEDG---ILRLY--------SMRFCPFAQRVHLVLDAKQIPYHSIYINLTDKPEW 60
            :|...|:..:.|:.   ::.|:        |:..|||:||:.::|..|.:.:....::|..||..
Mouse     1 MALSMPLNGLKEEDKEPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPAD 65

  Fly    61 LLEKNPQGKVPALEIVREPGPPVLTESLLICEYLDEQYPLRP-----LYPRDPLKKVQDKLLIER 120
            |....|....|.:....|    |.|:...|.|:|:|  .|.|     |.|:.|........:..:
Mouse    66 LQNLAPGTHPPFITFNSE----VKTDVNKIEEFLEE--VLCPPKYLKLSPKHPESNTAGMDIFAK 124

  Fly   121 FRAVLGAFFKASDGGDLEPFWSGL-----------------DIYEREL------ARRGTEFFGGE 162
            |    .|:.|.|.....|....||                 :|.|..:      .||   |..|:
Mouse   125 F----SAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRR---FLDGD 182

  Fly   163 QTGILDYMIWPWCERLELLKLQRGEDYNYD 192
            :..:.|..:.|   :|.::|:...:..|:|
Mouse   183 EMTLADCNLLP---KLHIVKVVAKKYRNFD 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
se	NP_648235.1	GST_N_Omega	3..95	CDD:239353	23/98 (23%)
		GST_C_Omega	109..229	CDD:198293	19/107 (18%)
Clic4	NP_038913.1	Required for insertion into the membrane. /evidence=ECO:0000250	2..101		26/104 (25%)
		O-ClC	17..252	CDD:129941	46/209 (22%)
		G-site. /evidence=ECO:0000250|UniProtKB:Q9Z0W7	35..38		2/2 (100%)