DRSC/TRiP Functional Genomics Resources

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Protein Alignment GstO3 and CLIC3

DIOPT Version :9

Sequence 1:NP_648234.1 Gene:GstO3 / 38972 FlyBaseID:FBgn0035904 Length:241 Species:Drosophila melanogaster
Sequence 2:NP_004660.2 Gene:CLIC3 / 9022 HGNCID:2064 Length:236 Species:Homo sapiens


Alignment Length:226 Identity:50/226 - (22%)
Similarity:87/226 - (38%) Gaps:68/226 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 DDGVLRLYSMRFCPYAQRAHLVLNAKNVPYHSVYINLTEKPEWLVEVSPLLKVPALQLVAEKGEP 82
            :||    .|:..||..||..:||..|.||:....::....|:.|.:.:|..::|.|...::    
Human    14 EDG----ESVGHCPSCQRLFMVLLLKGVPFTLTTVDTRRSPDVLKDFAPGSQLPILLYDSD---- 70

  Fly    83 SLIESLIIAEYLDDKY--PENPLLP---------------------KDPLKRAQDKILLERFSSI 124
            :..::|.|.::|::..  |:.|.|.                     |:|:. |||:.|.::    
Human    71 AKTDTLQIEDFLEETLGPPDFPSLAPRYRESNTAGNDVFHKFSAFIKNPVP-AQDEALYQQ---- 130

  Fly   125 TSAFINILVQGTGLEDYWTALDIFEEELTKRGTPYFGGNKPGFVDYMIWPWFERLSVIELKLQKE 189
               .:..|.:   |:.|..|  ..|.||.  |.|....::..|:|      .:||::.:..|   
Human   131 ---LLRALAR---LDSYLRA--PLEHELA--GEPQLRESRRRFLD------GDRLTLADCSL--- 176

  Fly   190 YNFNESRFPKITKWIALLKADSVVQSFYATP 220
                   .||      |...|:|...|...|
Human   177 -------LPK------LHIVDTVCAHFRQAP 194

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GstO3NP_648234.1 Thioredoxin_like 3..95 CDD:294274 19/76 (25%)
GstA 22..209 CDD:223698 44/209 (21%)
GST_C_Omega 109..230 CDD:198293 25/112 (22%)
CLIC3NP_004660.2 Required for insertion into the membrane. /evidence=ECO:0000250 1..88 20/81 (25%)
PLN02817 5..229 CDD:330276 50/226 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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