DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstO3 and CAM1

DIOPT Version :9

Sequence 1:	NP_648234.1	Gene:	GstO3 / 38972	FlyBaseID:	FBgn0035904	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_015277.1	Gene:	CAM1 / 856059	SGDID:	S000005969	Length:	415	Species:	Saccharomyces cerevisiae

Alignment Length:	178	Identity:	44/178 - (24%)
Similarity:	67/178 - (37%)	Gaps:	43/178 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 PLLKVPALQLVAEKGEPSLIESLIIAEYL-----DDKYPENPLLPKDPLKRAQDKILLERFSSIT 125
            ||.||||  .|..||. .|.|::.|..||     |||. :..||..|....||.:|:  |:.|:.
Yeast    45 PLKKVPA--FVGPKGY-KLTEAMAINYYLVKLSQDDKM-KTQLLGADDDLNAQAQII--RWQSLA 103

  Fly   126 SAFINILVQGT-----------------GLEDYWTALDIFEEELTKRGTPYFGGNKPGFVDY--- 170
            ::.:.|.:..|                 .::.....:||||..|  :...|.........|.
Yeast   104 NSDLCIQIANTIVPLKGGAPYNKKSVDSAMDAVDKIVDIFENRL--KNYTYLATENISLADLVAA 166

  Fly   171 -MIWPWFERLSVIELKLQKEYNFNESRFPKITKWIALLKADSVVQSFY 217
             :...:||.|...|.:.|         .|.|.:|...::|...::..|
Yeast   167 SIFTRYFESLFGTEWRAQ---------HPAIVRWFNTVRASPFLKDEY 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstO3	NP_648234.1	Thioredoxin_like	3..95	CDD:294274	14/33 (42%)
		GstA	22..209	CDD:223698	42/168 (25%)
		GST_C_Omega	109..230	CDD:198293	24/130 (18%)
CAM1	NP_015277.1	GST_N_EF1Bgamma	4..73	CDD:239342	14/30 (47%)
		GST_C_EF1Bgamma_like	92..214	CDD:198290	24/127 (19%)
		EF1G	255..359	CDD:395522
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345039
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930