DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstO3 and gsto1

DIOPT Version :9

Sequence 1:	NP_648234.1	Gene:	GstO3 / 38972	FlyBaseID:	FBgn0035904	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_001011256.1	Gene:	gsto1 / 496704	XenbaseID:	XB-GENE-5771576	Length:	241	Species:	Xenopus tropicalis

Alignment Length:	247	Identity:	95/247 - (38%)
Similarity:	135/247 - (54%)	Gaps:	23/247 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KHLAKGSPKPVLPDDGVLRLYSMRFCPYAQRAHLVLNAKNVPYHSVYINLTEKPEWLVEVSPLLK 69
            |.||||||.|....|||:|.|.|||||:||||||:|.||.:.:..||||...||:|..|.||..:
Frog     6 KSLAKGSPAPGPVPDGVIRAYIMRFCPFAQRAHLILVAKGIKHELVYINTLNKPDWFFEKSPFGQ 70

  Fly    70 VPALQLVAEKGEPSLIESLIIAEYLDDKYPENPLLPKDPLKRAQDKILLERFSSITSAFINILVQ 134
            |||::  ..||: .:.||.|:.:|||:.:|...|.|:||.::||.|:|||.||..::....|:..
Frog    71 VPAIE--TSKGQ-LIYESQIVCDYLDEVFPGKKLTPQDPFQKAQQKMLLEHFSKASTVAFKIVGA 132

  Fly   135 GTGLED-------YWTALDIFEEELTKRGTPYFGGNKPGFVDYMIWPWFERLSVIELK--LQKEY 190
            ....||       :...|..|::.:.|..|||.||:.....||||.|.|||..:..:|  |:|.
Frog   133 KKNNEDISALKAEFLEKLVQFDQVVAKLNTPYVGGSSVSMADYMILPIFERFDIFGVKDCLEKT- 196

  Fly   191 NFNESRFPKITKWIALLKADSVVQSFYATPEQHNEFWRTRKAGN---ANYDL 239
                   |.:.:|..|:..|..|::.:..||....|::....||   .:||:
Frog   197 -------PHLLQWYQLMLQDPAVKATHIKPEALEGFFKLYLQGNPESVDYDI 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstO3	NP_648234.1	Thioredoxin_like	3..95	CDD:294274	46/89 (52%)
		GstA	22..209	CDD:223698	75/195 (38%)
		GST_C_Omega	109..230	CDD:198293	38/129 (29%)
gsto1	NP_001011256.1	GST_N_Omega	6..93	CDD:239353	46/89 (52%)
gsto1	NP_001011256.1	GST_C_Omega	107..229	CDD:198293	38/129 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	84	1.000	Domainoid score	I8115
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	164	1.000	Inparanoid score	I4074
OMA	1	1.010	-	-		QHG48297
OrthoDB	1	1.010	-	-		D1225872at2759
OrthoFinder	1	1.000	-	-		FOG0001358
OrthoInspector	1	1.000	-	-		mtm9331
Panther	1	1.100	-	-	O	PTHR43968
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16830
SonicParanoid	1	1.000	-	-		X130
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.110