DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstO3 and gsto2

DIOPT Version :9

Sequence 1:	NP_648234.1	Gene:	GstO3 / 38972	FlyBaseID:	FBgn0035904	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_001007373.1	Gene:	gsto2 / 492500	ZFINID:	ZDB-GENE-041114-67	Length:	240	Species:	Danio rerio

Alignment Length:	248	Identity:	101/248 - (40%)
Similarity:	136/248 - (54%)	Gaps:	24/248 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SSGKHLAK--GSPKPVLPDDGVLRLYSMRFCPYAQRAHLVLNAKNVPYHSVYINLTEKPEWLVEV 64
            ||.|.|.|  .:|.||  .:|.:|||||||||:|||..|||.||.|.:..:.|||..||:|.::.
Zfish     3 SSPKCLGKECSAPGPV--PNGQIRLYSMRFCPFAQRTRLVLTAKGVKHDIININLVSKPDWFLKK 65

  Fly    65 SPLLKVPALQLVAEKGEPSLIESLIIAEYLDDKYPENPLLPKDPLKRAQDKILLERFSSITSAFI 129
            :|...||.|:  ...|: .:.||.|..||||:.|||..|||.||.:|||.|:|||.:|.:...|.
Zfish    66 NPFGTVPVLE--TSSGQ-VIYESPITCEYLDEVYPEKKLLPSDPFERAQQKMLLELYSKVIPYFY 127

  Fly   130 NILVQGTGLEDYWTALDIFEEE-------LTKRGTPYFGGNKPGFVDYMIWPWFERLSVIELK-- 185
            .|.:.....||..||...|.|:       |..:.|.||||:....:||:|||||||..::.:|
Zfish   128 KISMGKKRGEDVSTAEAEFTEKLLQLNEALANKKTKYFGGDSITMIDYLIWPWFERAEMMGVKHC 192

  Fly   186 LQKEYNFNESRFPKITKWIALLKADSVVQSFYATPEQHNEFWRTRKAGNANYD 238
            |.|.        |::.|||.|:..|.||::.....:.|..|:.:...|..|||
Zfish   193 LAKT--------PELRKWIELMFEDPVVKATMFNTDVHKVFFDSYMDGKPNYD 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstO3	NP_648234.1	Thioredoxin_like	3..95	CDD:294274	42/93 (45%)
		GstA	22..209	CDD:223698	83/195 (43%)
		GST_C_Omega	109..230	CDD:198293	44/129 (34%)
gsto2	NP_001007373.1	GST_N_Omega	4..93	CDD:239353	42/93 (45%)
		GstA	25..210	CDD:223698	82/195 (42%)
		GST_C_Omega	107..229	CDD:198293	44/129 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	92	1.000	Domainoid score	I7573
eggNOG	1	0.900	-	-		E1_KOG0406
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37971
Inparanoid	1	1.050	180	1.000	Inparanoid score	I3986
OMA	1	1.010	-	-		QHG48297
OrthoDB	1	1.010	-	-		D1225872at2759
OrthoFinder	1	1.000	-	-		FOG0001358
OrthoInspector	1	1.000	-	-		mtm6382
orthoMCL	1	0.900	-	-		OOG6_100366
Panther	1	1.100	-	-	O	PTHR43968
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16830
SonicParanoid	1	1.000	-	-		X130
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.870