DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GstO3 and gsto-3

DIOPT Version :9

Sequence 1:	NP_648234.1	Gene:	GstO3 / 38972	FlyBaseID:	FBgn0035904	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_741069.1	Gene:	gsto-3 / 175196	WormBaseID:	WBGene00019636	Length:	309	Species:	Caenorhabditis elegans

Alignment Length:	235	Identity:	85/235 - (36%)
Similarity:	126/235 - (53%)	Gaps:	22/235 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LAKGSPKPVLPDDGVLRLYSMRFCPYAQRAHLVLNAKNVPYHSVYINLTEKPEWLVEVSPLLKVP 71
            |..||.:|.| ..|..|||||||||||||..:.|..||:|...|.:|....|.|.:..||:.:||
Worm    85 LHPGSIEPPL-TPGNYRLYSMRFCPYAQRVLIYLAKKNIPVEVVNVNPDRSPNWYLPKSPIGRVP 148

  Fly    72 ALQLVAEKGEPSLIESLIIAEYLDDKYPENPLLPKDPLKRAQDKILLERFSSITSAFI------- 129
            ||::..:    .:.||.:|.||||:.:|.|.:||:|..::|..|||:||.|.|.:|..
Worm   149 ALEINGK----VVWESNVIVEYLDELFPTNTILPRDAYEKAHQKILVERLSPIMNALFEFYGSSN 209

  Fly   130 NILVQGTGLEDYWTALDIFEEELTKRGTPYFGGNKPGFVDYMIWPWFERLSVIELKLQKEYN-FN 193
            |...|.....:..:||...|..|  |.| ::||.:||:.||::||:.|||.::.:....::. |.
Worm   210 NPQAQRQNDMNVHSALRNSENLL--RDT-FYGGRQPGYADYLMWPFLERLQLLTMSPNSQFRYFP 271

  Fly   194 ESRFPKITKWIALLKADSVVQSFYATPEQHNEFWRTRKAG 233
            ...:|||..:||.::....|..|.    :|:.|  .:|.|
Worm   272 GLHYPKIGAYIARMQNQPEVLGFC----KHDFF--LKKTG 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstO3	NP_648234.1	Thioredoxin_like	3..95	CDD:294274	38/87 (44%)
		GstA	22..209	CDD:223698	73/194 (38%)
		GST_C_Omega	109..230	CDD:198293	38/128 (30%)
gsto-3	NP_741069.1	GST_N_Omega	81..168	CDD:239353	38/87 (44%)
gsto-3	NP_741069.1	GST_C_Omega	182..308	CDD:198293	40/133 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	43	1.000	Domainoid score	I8399
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37971
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.71939	Normalized mean entropy	S4834
OMA	1	1.010	-	-		QHG48297
OrthoDB	1	1.010	-	-		D1225872at2759
OrthoFinder	1	1.000	-	-		FOG0001358
OrthoInspector	1	1.000	-	-		mtm4834
orthoMCL	1	0.900	-	-		OOG6_100366
Panther	1	1.100	-	-	O	PTHR43968
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16830
SonicParanoid	1	1.000	-	-		X130
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.910