DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6765 and chinmo

DIOPT Version :9

Sequence 1:	NP_001261582.1	Gene:	CG6765 / 38971	FlyBaseID:	FBgn0035903	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	NP_001188680.1	Gene:	chinmo / 33343	FlyBaseID:	FBgn0086758	Length:	840	Species:	Drosophila melanogaster

Alignment Length:	777	Identity:	172/777 - (22%)
Similarity:	277/777 - (35%)	Gaps:	232/777 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ENYHLKWDSHLTYLNSSIATLYKNEKFADVVLYSSYNSSGIPSDIPTVGISAHKFILSASSQFFA 68
            :.:.|||:|..:.|..:.:.|:|::..|||:|    :..|       |...|||.||:|.|:.||
  Fly     5 QQFCLKWNSFSSNLAITFSNLFKSDLLADVIL----SCDG-------VVFKAHKLILAACSKKFA 58

  Fly    69 TMFETAPITNPNGVLYVVL---PPDLSHRAIQILVQYMYSGEATVSNDILNEVLRGGEILKIRGL 130
            .:||..|   .||...::|   .||    .:..|:::||.||..||.:.||..|:..|.|:::||
  Fly    59 DLFENTP---TNGQCVIILEATTPD----NMAALLEFMYKGEVHVSQEALNSFLKSAESLQVKGL 116

  Fly   131 CRTSSSNGGGSGSVVTTTHHPHSLAGHLHPREAST------MYMSNGTRTALPPPPPPPQSTMSA 189
                |:..|...:.....|     .|.|.|.::.|      ..:|.|:.:.:|
  Fly   117 ----STETGRLAAQQAQQH-----MGDLSPLDSPTGRRSVRNSLSGGSSSIVP------------ 160

  Fly   190 QLQGDLYASKPGGSTRFALDHHHLSSHHSHLNHHNPQQQFRGLGASVMPKDSPVIIKSPKLAAHT 254
               |.:.....||:|.        ::..|.:...|      ||..:.|.....:...:.  ||.:
  Fly   161 ---GGVGIGLGGGATG--------ANSMSGMGIGN------GLSLAGMAAGGGMAAAAN--AAAS 206

  Fly   255 GLLTVASSSKLGISVNKEVAIDPEDKCCFAAPGQLESQ------SHPPPPTTTTTTVGGGGGSVG 313
            .|.|:|:|:.:            .|:|..|....:...      ||.......:.|||.||..|
  Fly   207 SLSTLAASANI------------VDRCGSAGANIISGSAAGIGGSHSGGAGNGSGTVGIGGNGV- 258

  Fly   314 GSGAPPSQPISICTEVGCS------------SCPLTAGPGADQAETTL---------RRTEYEEQ 357
            |||...:.|||:.:..|.:            .|.....||...:.:.:         |...||..
  Fly   259 GSGGGNNGPISLGSGAGAAHHLGGSTGILKQECDSLMHPGGSSSSSGMGYTHVPPIYRPINYEPP 323

  Fly   358 ALRERNEVGLVFERRLRRESACERSRDYYEAPHFEHVVSSRLAATPPPPPQQAPPSHPP----TL 418
                             |:.|..|| .|.|......|:.....::..|.|...||.|.|    :.
  Fly   324 -----------------RKRAIVRS-PYSEQEQRGSVLRDGSKSSECPSPINKPPYHRPSSSASS 370

  Fly   419 RHPHNFLTIKQE-----PTDWSNNPPNASSASNN--NNLEELPLASPKQPLDFKMSAVKLEVNRD 476
            ..|....|:..|     .:.:.|:.|:.::.:.|  ::||.:               ||.|  |:
  Fly   371 TAPTEADTMHSERASPQSSRYENHSPSTTAGNGNATSSLERI---------------VKSE--RN 418

  Fly   477 RGTPSEESEEHTLRDYNNFKQLLVCEICQKSFEDTKMLVRHLGTHAGDPTGGTERNLLPSSASGS 541
            .|:.:|.:::         .:.|:.|......||.::.:.:|......|         |:|.:.|
  Fly   419 NGSANEANDD---------DRELMDESTDNGAEDLRVKLENLKYSPPPP---------PNSNTSS 465

  Fly   542 TT------------SASSNLAL-------------------RSVKTYVPKKRR-----RVSQQEN 570
            ||            :.|||||.                   .||.|...||.:     |:...|.
  Fly   466 TTPNTLLENLKADGTLSSNLAASIAPADMLNVWNATKMNNKNSVNTADGKKLKCLYCDRLYGYET 530

  Fly   571 NM------DHDHVTLLCDLCSTSFDTPAEWVRHMNSQH-TEIEL--------------AMFNSKK 614
            |:      .|..:.:.|..|..:|.......||:..:| .||.|              |..::..
  Fly   531 NLRAHIRQRHQGIRVPCPFCERTFTRNNTVRRHIAREHKQEIGLAAGATIAPAHLAAAAAASAAA 595

  Fly   615 DGEQKGQQPPPPPATSSSSTVSNSQMQPKYPSSTATRSTHSLMLHK-MSNSDAVATTTSPGA 675
            ........| ...||:::|.|.|:.   |..:....|.|..:.|.| |...||:...|:.||
  Fly   596 TAAASNHSPXEAAATAAASVVMNAN---KEAAKQRKRKTLKMALEKCMQRRDAMVAETTTGA 654

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6765	NP_001261582.1	BTB	24..132	CDD:279045	39/110 (35%)
CG6765	NP_001261582.1	BTB	53..130	CDD:197585	29/79 (37%)
chinmo	NP_001188680.1	BTB	22..116	CDD:279045	37/111 (33%)
		BTB	33..116	CDD:197585	34/100 (34%)
		C2H2 Zn finger	519..540	CDD:275368	3/20 (15%)
		C2H2 Zn finger	547..568	CDD:275368	5/20 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010