DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6765 and CG3726

DIOPT Version :9

Sequence 1:	NP_001261582.1	Gene:	CG6765 / 38971	FlyBaseID:	FBgn0035903	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	NP_001284917.1	Gene:	CG3726 / 31525	FlyBaseID:	FBgn0029824	Length:	682	Species:	Drosophila melanogaster

Alignment Length:	475	Identity:	105/475 - (22%)
Similarity:	152/475 - (32%)	Gaps:	162/475 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAAENYHLKWDSHLTYLNSSIATLYKNEKFADVVLYSSYNSSGIPSDIPTVGISAHKFILSASSQ 65
            |..:.|.|:|..|.:.|.:..:.|.....|.||.|......           |.||:.:|.|.|.
  Fly     1 MLPQQYCLRWKYHHSNLQTMFSQLLDRGCFCDVTLACEGQL-----------IRAHRVVLCACST 54

  Fly    66 FF-ATMFETAPITNPNGVLYVVLPPDLSHRAIQILVQYMYSGEATVSNDILNEVLRGGEILKIRG 129
            || |.:...|...:|     :::..|::...::.|:::||.||..|.:..|..:|:..:.|||:|
  Fly    55 FFDAVLSNYASERDP-----IIIMKDVTFAEVKCLIEFMYKGEINVEHSSLPSLLKTADDLKIKG 114

  Fly   130 LCRTS---SSNGGGSGSVVTTTHHPHSLAGHLHPREASTMYMSNGTRTALPPPP-------PPPQ 184
            |...:   ..:|                                      ||||       .||:
  Fly   115 LAEVTWRDDEDG--------------------------------------PPPPMAAAEFHSPPR 141

  Fly   185 STMSAQLQGDLYASKPGGSTRFALDHHHLSSHHSHLNHHNPQQQFRGLGASVMPKDSPVIIKSPK 249
            |...:..| ||.                       |.|...|||            .|.   :|.
  Fly   142 SLAESYAQ-DLI-----------------------LQHQQQQQQ------------GPA---APP 167

  Fly   250 LAAHTGLLTVASSSKLGISVNKEVAIDPEDKCCFAAPGQLESQSHPPPPTTTTTTVGGGG-GSVG 313
            |..|      :|::.|.....:|...|.|.    .:||........|..|..|...|..| |||.
  Fly   168 LNLH------SSAALLERDRERERERDRER----LSPGMEGVLGRMPVMTPLTGASGSAGVGSVS 222

  Fly   314 G----SGAPPSQPISICTEVGCSSCPLTAGPGADQAETTLRRTEYEEQALRERNEVGLVFERRLR 374
            |    .|..|.:..              .||...:....|             ::...||..|..
  Fly   223 GGTSLEGVAPVEHF--------------LGPKRKRGRPPL-------------DDAYDVFNVRKL 260

  Fly   375 RESACE---RSRDYYE-APHF-EHVVSSRLAATPPPPPQQAPPSHPPTLRHP--------HNFLT 426
            .:.|..   ..|.|.| |.|| |....:..||:...||...||.....|||.        .:..:
  Fly   261 AQYAANLEPAQRAYLETARHFTEEPPLAAHAASMASPPAACPPKQRQRLRHQQQQQQQLLQSESS 325

  Fly   427 IKQEPT---DWSNNPPNASS 443
            .:::|.   ||||..||.|:
  Fly   326 DQEQPAAGQDWSNLEPNGSA 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6765	NP_001261582.1	BTB	24..132	CDD:279045	30/108 (28%)
CG6765	NP_001261582.1	BTB	53..130	CDD:197585	23/77 (30%)
CG3726	NP_001284917.1	BTB	21..118	CDD:279045	30/112 (27%)
		BTB	32..121	CDD:197585	28/104 (27%)
		HTH_psq	587..622	CDD:283007
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451871
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940